Genetic Polymorphism and type 2 diabetes
Kiran BalaSeema Joshi
Broschiertes Buch

Genetic Polymorphism and type 2 diabetes

Genetic Polymorphism of NLRP3, C5L2 and PRKCZ genes and risk of type of T2DM

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T2DM is a leading disease in the human people throughout the world, mainly in developing countries with an incidence of 9.3% (Buse et al, 2020). It is characterized by a chronically elevated high blood glucose level due to impairment in insulin action, insulin secretion or both and dysregulation of protein and lipid metabolism. Other factor responsible for pathogenesis of T2DM are combined action of environmental, dietary, behavioral and genetic risk factors which play a major role in describing the susceptibility causes of type 2 diabetes mellitus (Gloyn et al, 2018).T2DM is mainly linked wit...