Gareth Thomas

Fundamentals of Medicinal Chemistry

• Broschiertes Buch

Produktbeschreibung

Medizinische Chemiker beschäftigen sich mit der Erforschung therapeutisch aktiver Verbindungen. Eine Einführung in dieses Gebiet, das mittlerweile auch vielfach im Grundstudium behandelt wird, bietet Ihnen dieser handliche Band. Neben Grundlagen werden viele Anwendungsbeispiele behandelt; Übungsaufgaben (teils mit Lösungen) erleichtern das Umsetzen des Stoffes in die Praxis.

Produktdetails

• Verlag: Wiley & Sons
• 1. Auflage
• Seitenzahl: 302
• Erscheinungstermin: 29. Oktober 2003
• Englisch
• Abmessung: 246mm x 189mm x 16mm
• Gewicht: 675g
• ISBN-13: 9780470843079
• ISBN-10: 0470843071
• Artikelnr.: 11747216

Autorenporträt

Gareth Thomas is a lecturer at the University of Portsmouth.

Inhaltsangabe

Preface. Acknowledgements. Abbreviations/Acronyms. 1. Biological Molecules.
2. An Introduction to Drugs and Their Action. 3. An Introduction to Drug
Discovery. 4. The SAR and QSAR Approaches to Drug Design. 5. Computer Aided
Drug Design. 6. Combinatorial Chemistry. 7. Selected Examples of Drug
Action at some Common Target Areas. 8. Pharmacokinetics. 9. Drug
Metabolism. 10. An Introduction to Lead and Analogue Syntheses. 11. Drug
Development and Production. Appendix 1. Sickle-cell Anaemia. Appendix 2.
Bacteria. Appendix 3. Cell Membranes. Appendix 4. Receptors. Appendix 5.
Transfer through Membranes. Appendix 6. Regression Analysis. Appendix 7.
Enzymes. Answers to Questions. Selected Further Reading. Index.

Rezensionen

"...provides a concise introduction to the chemistry of therapeutically active compounds, written in a readable and accessible style..." (www.organische-chemie.ch, 19/01/2004)

"...it would be of great value to beginning graduate students in medicinal chemistry...it should be included in any practicing chemist's personal library." (Journal of Medicinal Chemistry, July 29, 2004)

"Thomas presents the fundamentals of medicinal chemistry in a clear, concise, and descriptive fashion." (Choice, June 2004, Vol. 41 No. 10)

"...provides a concise introduction to the chemistry of therapeutically active compounds, written in a readable and accessible style..." (www.organische-chemie.ch, 19/01/2004)

"...well laid out, with an attractive typeface." (Chemistry and Industry, 6th September 2004)