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This work focuses on the compilation of data on four medicinal plants present in the state of Durango, Mexico, exploring their traditional uses and therapeutic potential. Through research and collection of traditional knowledge, numerous plant species used by local communities to treat a variety of ailments and diseases are identified, that is why we focus on four of the plants with the greatest therapeutic potential; which are: Arnica Montana, Llantén Mayor, Mezquite and Pasionaria.