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This issue of Neuroimaging Clinics of North America focuses on fMRI for the Diagnosis, Treatment and Management of Brain Tumors and is edited by Dr. Andrei I. Holodny. Articles will include: Introduction to fMRI; How to start your clinical fMRI program; Diffusion tractography; The problem of neurovascular uncoupling; Dynamic Resting State fMRI; Resting State fMRI of language function; Methods of fMRI analysis; Patient preparation and fMRI paradigm design; Functional brain anatomy; Neurosurgical Applications of fMRI; and more!