Fatal Attractions: Protein Aggregates in Neurodegenerative Disorders

Herausgegeben:Lee, V.M.-Y.; Trojanowski, J. Q.; Buee, L.; Christen, Y.

• Broschiertes Buch

Produktbeschreibung

In this volume are contributions based on a meeting arranged by the WHO and the Fondation IPSEN. The scientists focus on neurodegenerative disorders like Alzheimer's Disease, Chromosome 17-Linked Dementia, Parkinson's Disease and disorders with tauopathies.

Produktdetails

• Research and Perspectives in Alzheimer's Disease
• Verlag: Springer / Springer Berlin Heidelberg / Springer, Berlin
• Artikelnr. des Verlages: 978-3-642-08649-6
• Softcover reprint of hardcover 1st ed. 2000
• Seitenzahl: 156
• Erscheinungstermin: 1. Dezember 2010
• Englisch
• Abmessung: 235mm x 155mm x 9mm
• Gewicht: 248g
• ISBN-13: 9783642086496
• ISBN-10: 3642086497
• Artikelnr.: 32055412

Inhaltsangabe

The Role of ?-Synuclein in Parkinson's Disease: A Biophysical Analogy to A? and Alzheimer's Disease.- Purification of Lewy Bodies and Identification of ? -Synuclein as a Major Component of Lewy Bodies.- Mutational Analysis of Tau in Chromosome 17-Linked Dementia.- Missense and Splice Site Mutations in Tau Associated with FTDP-17: Multiple Pathogenic Mechanisms.- Tau Mutations: Genetics and Pathogenetic Mechanisms.- Tauopathies and ?-Synucleinopathies.- Distinct Tau Gene Mutations Induce Specific Dysfunctions/Toxic Properties in Tau Proteins Associated with Specific FTDP-17 Phenotypes.- Neurodegenerative Disorders with Tauopathies: Mad Tau Diseases?.- Tau Protein: Role in Intracellular Traffic and Development of Cell Polarity.