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The HIV/AIDS is among devastating epidemics around the World; but it emphasizes on the case of Rwanda where the use of Demographic Health Survey(DHS) data enable us to know its infection among individual background characteristics with the main objective of identifying its potential risk factor in Rwanda. The results shows that the potential risk factors for HIV/AIDS in Rwanda are province and place of residence. Generally, the HIV/AIDS prevalence of 3% has to be reduced. For this reason the government and the health communities in charge of HIV/AIDS have to instruct people about the transmission and prevention of HIV/AIDS in order to reduce the risk of being infected. Also, the impact analysis to determine Quality of care as a key factor to the success of HIV response has to be conducted.