Front matter Contributors Contents Introduction to experimental toxicology Effects of physical form, route, and species Influence of animal species, strain, age, hormonal, and nutritional status Experimental design The biochemical principles of toxicology Animal husbandry Inhalation toxicology Histopathology in safety evaluation The metabolism and dispostion of xenobiotics Theory and practice in metabolic studies ImmunotoxicologyùConceptual problems Perspectivesù the evaluation of reproductive toxicity and teratogenicity Genetic toxicology Molecular toxicology Testing for carcinogenicity In vitro methods for teratology testing Assessing chemical injury to the reproductive system Statistics Risk assessment of chemicals Epidemiology Information and consultancy services in toxicology Regulations and advisory requirements in relation to food The influence of a growing environmental awareness on laboratory design Good laboratory practice Ethics in experiments on animals Index
Front matter Contributors Contents Introduction to experimental toxicology Effects of physical form, route, and species Influence of animal species, strain, age, hormonal, and nutritional status Experimental design The biochemical principles of toxicology Animal husbandry Inhalation toxicology Histopathology in safety evaluation The metabolism and dispostion of xenobiotics Theory and practice in metabolic studies ImmunotoxicologyùConceptual problems Perspectivesù the evaluation of reproductive toxicity and teratogenicity Genetic toxicology Molecular toxicology Testing for carcinogenicity In vitro methods for teratology testing Assessing chemical injury to the reproductive system Statistics Risk assessment of chemicals Epidemiology Information and consultancy services in toxicology Regulations and advisory requirements in relation to food The influence of a growing environmental awareness on laboratory design Good laboratory practice Ethics in experiments on animals Index
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