Evidence-Based Dermatology
Herausgegeben von Williams, Hywel; Bigby, Michael; Herxheimer, Andrew; Naldi, Luigi; Rzany, Berthold
Evidence-Based Dermatology
Herausgegeben von Williams, Hywel; Bigby, Michael; Herxheimer, Andrew; Naldi, Luigi; Rzany, Berthold
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Be sure your skin-care treatments have strong evidentialsupport
Evidence-based Dermatology, Third Edition takes a uniqueapproach to clinical dermatology by emphasising use of only thehighest quality available evidence when treating people with skindiseases.
Beginning with a toolbox introduction to the practice ofevidence-based dermatology, it then covers the application ofevidence for dermatological treatments across a wide range ofailments, including:
- Common inflammatory skin diseases
- Skin cancer, moles and actinic keratoses
- Infective skin disease, exanthems and…mehr
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Be sure your skin-care treatments have strong evidentialsupport
Evidence-based Dermatology, Third Edition takes a uniqueapproach to clinical dermatology by emphasising use of only thehighest quality available evidence when treating people with skindiseases.
Beginning with a toolbox introduction to the practice ofevidence-based dermatology, it then covers the application ofevidence for dermatological treatments across a wide range ofailments, including:
- Common inflammatory skin diseases
- Skin cancer, moles and actinic keratoses
- Infective skin disease, exanthems and infestations
- Disorders of pigmentation
In addition, many of the rarer skin disorders are also includedso as to provide comprehensive coverage of the topic.
World-leading experts in dermatology follow a clinical approachfor each disease, and as well as providing their expert guidance onthe description and diagnosis of dermatologic disorders, they alsodiscuss common dilemmas that clinicians face when considering thebest approach to patient management. 'Key Points'accompany each chapter to provide a quick review of the mostimportant points.
Clinically oriented and practically focused, Evidence-basedDermatology ensures that your treatments are entirelypatient-focused and fully supported by the very latest medicalevidence.
Evidence-based Dermatology, Third Edition takes a uniqueapproach to clinical dermatology by emphasising use of only thehighest quality available evidence when treating people with skindiseases.
Beginning with a toolbox introduction to the practice ofevidence-based dermatology, it then covers the application ofevidence for dermatological treatments across a wide range ofailments, including:
- Common inflammatory skin diseases
- Skin cancer, moles and actinic keratoses
- Infective skin disease, exanthems and infestations
- Disorders of pigmentation
In addition, many of the rarer skin disorders are also includedso as to provide comprehensive coverage of the topic.
World-leading experts in dermatology follow a clinical approachfor each disease, and as well as providing their expert guidance onthe description and diagnosis of dermatologic disorders, they alsodiscuss common dilemmas that clinicians face when considering thebest approach to patient management. 'Key Points'accompany each chapter to provide a quick review of the mostimportant points.
Clinically oriented and practically focused, Evidence-basedDermatology ensures that your treatments are entirelypatient-focused and fully supported by the very latest medicalevidence.
Produktdetails
- Produktdetails
- Evidence-Based Medicine
- Verlag: Wiley & Sons
- 3. Aufl.
- Seitenzahl: 680
- Erscheinungstermin: 11. August 2014
- Englisch
- Abmessung: 285mm x 221mm x 32mm
- Gewicht: 1880g
- ISBN-13: 9781118357675
- ISBN-10: 1118357671
- Artikelnr.: 40134156
- Evidence-Based Medicine
- Verlag: Wiley & Sons
- 3. Aufl.
- Seitenzahl: 680
- Erscheinungstermin: 11. August 2014
- Englisch
- Abmessung: 285mm x 221mm x 32mm
- Gewicht: 1880g
- ISBN-13: 9781118357675
- ISBN-10: 1118357671
- Artikelnr.: 40134156
Hywel Williams, MBBS Department of Dermatology, Queen's Medical Centre, University of Nottingham, Nottingham, UK. Michael Bigby, MD, Department of Dermatology, Harvard Medical School, USA. Andrew Herxheimer, MBBS, UK Cochrane Centre. Luigi Naldi, M, Department of Dermatology, Ospedali Riuniti, Bergamo, Italy. Berthold Rzany, MD, Division of EBM, Klinik fur Dermatologie, Charite-Universitatsmedizin, Berlin, Germany. Robert Dellavalle, MD, Chief, Dermatology Service, Denver VA Medical Center, USA. Yuping Ran, MD, Department of Dermatology, Sichuan University, China. Masutaka Furue, MD, Department of Dermatology, Kyushu University, Japan.
Contributors
viii Foreword
xii Preface
xiv About the companion website
xv PART I: The concept of evidence-based dermatology Andrew Herxheimer
editor 1 The field and its boundaries
3 Luigi Naldi 2 The rationale for evidence-based dermatology
7 Hywel C. Williams and Michael Bigby 3 The role of patient and public involvement in evidence-based dermatology
12 Carron Layfield
Amanda Roberts
Jason Simons
Colette O'Sullivan
Anjna Rani
and Kim Thomas 4 The Cochrane Skin Group
17 Finola Delamere
Liz Doney
Laura Prescott
and Shirley Manknell PART II: The critical appraisal toolbox Michael Bigby
editor 5 Formulating well-built clinical questions
25 Michael Bigby and Berthold Rzany 6 Finding the best evidence
27 Michael Bigby and Rosamaria Corona 7 The hierarchy of evidence
30 Michael Bigby 8 Appraising systematic reviews and meta-analyses
33 Michael Bigby and Hywel C. Williams 9 How to critically appraise a randomized controlled trial
39 Hywel C. Williams 10 Assessing and explaining the evidence on harms of medical interventions
46 Luigi Naldi 11 How to evaluate diagnostic tests
50 Joerg Albrecht and Michael Bigby 12 What makes a good case series?
54 Joerg Albrecht and Michael Bigby 13 What makes a good prevalence survey?
58 Hywel C. Williams 14 Critical appraisal of pharmacoeconomic studies
62 Rajini K. Murthy
Laura K. DeLong
and Suephy C. Chen 15 Comparative effectiveness research: what it is and how to assess its quality
66 Junko Takeshita and Joel M. Gelfand 16 Outcome measures
71 Alain Dupuy
Emilie Sbidian
and Sylvie Bastuji-Garin 17 Where does qualitative research fit into evidence-based dermatology?
75 Ray Jobling and Luigi Naldi 18 Applying the evidence back to the patient
79 Hywel C. Williams PART III: The evidence SECTION 1: Common inflammatory skin diseases Luigi Naldi
editor 19 Acne vulgaris
87 Michael Romano and Robert P. Dellavalle 20 Papulopustular rosacea
106 Alfredo Rebora and Francesco Drago 21 Perioral dermatitis
112 Vincenzo Bettoli
Stefania Zauli
and Annarosa Virgili 22 Hand eczema
117 Wietske A. Christoffers
Marie-Louise Anna Schuttelaar
and Pieter-Jan Coenraads 23 The primary prevention of atopic dermatitis
127 Joanne R. Chalmers
Sam F. Bremmer
and Eric L. Simpson 24 Atopic eczema
136 Kim Thomas
Carolyn Charman
Helen Nankervis
Jane Ravenscroft
and Hywel C. Williams 25 Seborrheic dermatitis
169 Mauro Picardo and Norma Cameli 26 Treatment of psoriasis
175 Alexander Nast
Phyllis Spuls
and Tamar Nijsten 27 Lichen planus
200 Laurence Le Cleach and Olivier Chosidow 28 Acute urticaria
206 Torsten Schafer 29 Chronic urticaria
210 Karsten Weller and Marcus Maurer SECTION 2: Skin cancer
moles
and actinic keratoses Robert Dellavalle
editor 30 Primary prevention of skin cancer
223 Monika Janda and Adele C. Green 31 Treatment of cutaneous melanoma
231 Mary Ann N. Johnson and April W. Armstrong 32 Treatment of squamous cell carcinoma
241 Louise Lansbury
William Perkins
and Fiona Bath-Hextall 33 Basal cell carcinoma
250 Fiona Bath-Hextall and William Perkins 34 Primary cutaneous T-cell lymphoma
264 Fiona Child and Sean Whittaker 35 Actinic keratosis and Bowen's disease
283 Sasha N. Jenkins
Maren Speck
and Suephy C. Chen 36 Kaposi sarcoma
303 Whitney A. High 37 Melanocytic nevi
313 Varun Shahi and Jerry D. Brewer SECTION 3: Infective skin diseases
exanthems
and infestations Masutaka Furue and Yuping Ran
editors 38 Local treatments for cutaneous warts
320 Juping Chen and Yan Wu 39 Molluscum contagiosum
329 Minh L. Lam 40 Impetigo
337 Sander Koning
Renske van der Sande
Lisette W.A. van Suijlekom-Smit
and Johannes C. van der Wouden 41 Athlete's foot
341 Inajara Rotta
Michel F. Otuki
and Cassyano J. Correr 42 Pityriasis versicolor
345 Nancy Habib and Michael Bigby 43 Onychomycosis
349 Aditya K. Gupta
Elizabeth A. Cooper
Maryse Paquet
and Fiona Simpson 44 Tinea capitis
364 Urba Gonzalez 45 Deep fungal infections
371 Roderick J. Hay 46 Streptococcal cellulitis/erysipelas of the lower leg
378 Vinod E. Nambudiri and Michael Bigby 47 Exanthematic reactions
388 Sandra R. Knowles and Neil H. Shear 48 Herpes simplex
396 Vera Mahler 49 Leprosy
407 Saumya Panda 50 Cutaneous leishmaniasis
421 Urba Gonzalez
Armando Ruiz-Baques
and Jorge Alvar 51 Scabies
432 Ian F. Burgess 52 Head lice
441 Ian F. Burgess and Ciara S. Casey 53 Insect bites and stings
451 Belen Lardizabal Dofitas SECTION 4: Disorders of pigmentation Hywel C. Williams
editor 54 Vitiligo
464 Juan Jorge Manriquez and Sergio M. Niklitschek 55 Melasma
470 Asad Salim
Ratna Rajaratnam
and Eva Soos Domanne SECTION 5: Common ailments with significant cosmetic impact Berthold Rzany
editor 56 Male and female androgenetic alopecia
486 Hans Wolff and Kathrin Giehl 57 Alopecia areata
490 Rod Sinclair 58 Evidence-based treatment of hirsutism
498 Ulrike Blume-Peytavi and Natalie Garcia-Bartels 59 Focal hyperhidrosis
504 Kave Shams and Berthold Rzany 60 Dermal fillers
512 Stephanie Ogden and Tamara Griffiths 61 Reducing mimic wrinkles and folds with botulinum toxin A
516 Berthold Rzany SECTION 6: Other important skin disorders Michael Bigby
editor 62 Cutaneous lupus erythematosus
523 Susan Jessop and David Whitelaw 63 Dermatomyositis
531 Ruth Ann Vleugels
David F. Fiorentino
and Jeffrey P. Callen 64 Acquired subepidermal bullous diseases
545 Gudula Kirtschig
Vanessa Venning
Nonhlanhla P. Khumalo
and Fenella Wojnarowska 65 Pemphigus
552 Linda K. Martin
Brian R. Sperber
Dedee F. Murrell
and Victoria P. Werth 66 Cutaneous sarcoidosis
561 Misha Rosenbach and Joseph C. English III 67 Erythema multiforme
575 Pierre-Dominique Ghislain and Jean-Claude Roujeau 68 Stevens-Johnson syndrome and toxic epidermal necrolysis
578 Jean-Claude Roujeau
Pierre-Dominique Ghislain
and Laurence Valleyrie-Allanore 69 Polymorphic light eruption
586 Robert S. Dawe 70 Infantile hemangiomas
590 Hossain Shahidullah 71 Pruritus
595 Elke Weisshaar and Gil Yosipovitch 72 Vulval lichen sclerosus
erosive lichen planus
and vulvodynia
615 Rosalind C. Simpson
Ruth Murphy
and David Nunns 73 Venous ulcers
624 Jonathan Kantor
David J. Margolis
and Douglas J. Pugliese 74 Other skin diseases for which trials exist
632 Sinead Langan and Hywel C. Williams PART IV: The future of evidence-based dermatology Luigi Naldi
editor 75 Where do we go from here?
637 Hywel C. Williams Subject Index
644
viii Foreword
xii Preface
xiv About the companion website
xv PART I: The concept of evidence-based dermatology Andrew Herxheimer
editor 1 The field and its boundaries
3 Luigi Naldi 2 The rationale for evidence-based dermatology
7 Hywel C. Williams and Michael Bigby 3 The role of patient and public involvement in evidence-based dermatology
12 Carron Layfield
Amanda Roberts
Jason Simons
Colette O'Sullivan
Anjna Rani
and Kim Thomas 4 The Cochrane Skin Group
17 Finola Delamere
Liz Doney
Laura Prescott
and Shirley Manknell PART II: The critical appraisal toolbox Michael Bigby
editor 5 Formulating well-built clinical questions
25 Michael Bigby and Berthold Rzany 6 Finding the best evidence
27 Michael Bigby and Rosamaria Corona 7 The hierarchy of evidence
30 Michael Bigby 8 Appraising systematic reviews and meta-analyses
33 Michael Bigby and Hywel C. Williams 9 How to critically appraise a randomized controlled trial
39 Hywel C. Williams 10 Assessing and explaining the evidence on harms of medical interventions
46 Luigi Naldi 11 How to evaluate diagnostic tests
50 Joerg Albrecht and Michael Bigby 12 What makes a good case series?
54 Joerg Albrecht and Michael Bigby 13 What makes a good prevalence survey?
58 Hywel C. Williams 14 Critical appraisal of pharmacoeconomic studies
62 Rajini K. Murthy
Laura K. DeLong
and Suephy C. Chen 15 Comparative effectiveness research: what it is and how to assess its quality
66 Junko Takeshita and Joel M. Gelfand 16 Outcome measures
71 Alain Dupuy
Emilie Sbidian
and Sylvie Bastuji-Garin 17 Where does qualitative research fit into evidence-based dermatology?
75 Ray Jobling and Luigi Naldi 18 Applying the evidence back to the patient
79 Hywel C. Williams PART III: The evidence SECTION 1: Common inflammatory skin diseases Luigi Naldi
editor 19 Acne vulgaris
87 Michael Romano and Robert P. Dellavalle 20 Papulopustular rosacea
106 Alfredo Rebora and Francesco Drago 21 Perioral dermatitis
112 Vincenzo Bettoli
Stefania Zauli
and Annarosa Virgili 22 Hand eczema
117 Wietske A. Christoffers
Marie-Louise Anna Schuttelaar
and Pieter-Jan Coenraads 23 The primary prevention of atopic dermatitis
127 Joanne R. Chalmers
Sam F. Bremmer
and Eric L. Simpson 24 Atopic eczema
136 Kim Thomas
Carolyn Charman
Helen Nankervis
Jane Ravenscroft
and Hywel C. Williams 25 Seborrheic dermatitis
169 Mauro Picardo and Norma Cameli 26 Treatment of psoriasis
175 Alexander Nast
Phyllis Spuls
and Tamar Nijsten 27 Lichen planus
200 Laurence Le Cleach and Olivier Chosidow 28 Acute urticaria
206 Torsten Schafer 29 Chronic urticaria
210 Karsten Weller and Marcus Maurer SECTION 2: Skin cancer
moles
and actinic keratoses Robert Dellavalle
editor 30 Primary prevention of skin cancer
223 Monika Janda and Adele C. Green 31 Treatment of cutaneous melanoma
231 Mary Ann N. Johnson and April W. Armstrong 32 Treatment of squamous cell carcinoma
241 Louise Lansbury
William Perkins
and Fiona Bath-Hextall 33 Basal cell carcinoma
250 Fiona Bath-Hextall and William Perkins 34 Primary cutaneous T-cell lymphoma
264 Fiona Child and Sean Whittaker 35 Actinic keratosis and Bowen's disease
283 Sasha N. Jenkins
Maren Speck
and Suephy C. Chen 36 Kaposi sarcoma
303 Whitney A. High 37 Melanocytic nevi
313 Varun Shahi and Jerry D. Brewer SECTION 3: Infective skin diseases
exanthems
and infestations Masutaka Furue and Yuping Ran
editors 38 Local treatments for cutaneous warts
320 Juping Chen and Yan Wu 39 Molluscum contagiosum
329 Minh L. Lam 40 Impetigo
337 Sander Koning
Renske van der Sande
Lisette W.A. van Suijlekom-Smit
and Johannes C. van der Wouden 41 Athlete's foot
341 Inajara Rotta
Michel F. Otuki
and Cassyano J. Correr 42 Pityriasis versicolor
345 Nancy Habib and Michael Bigby 43 Onychomycosis
349 Aditya K. Gupta
Elizabeth A. Cooper
Maryse Paquet
and Fiona Simpson 44 Tinea capitis
364 Urba Gonzalez 45 Deep fungal infections
371 Roderick J. Hay 46 Streptococcal cellulitis/erysipelas of the lower leg
378 Vinod E. Nambudiri and Michael Bigby 47 Exanthematic reactions
388 Sandra R. Knowles and Neil H. Shear 48 Herpes simplex
396 Vera Mahler 49 Leprosy
407 Saumya Panda 50 Cutaneous leishmaniasis
421 Urba Gonzalez
Armando Ruiz-Baques
and Jorge Alvar 51 Scabies
432 Ian F. Burgess 52 Head lice
441 Ian F. Burgess and Ciara S. Casey 53 Insect bites and stings
451 Belen Lardizabal Dofitas SECTION 4: Disorders of pigmentation Hywel C. Williams
editor 54 Vitiligo
464 Juan Jorge Manriquez and Sergio M. Niklitschek 55 Melasma
470 Asad Salim
Ratna Rajaratnam
and Eva Soos Domanne SECTION 5: Common ailments with significant cosmetic impact Berthold Rzany
editor 56 Male and female androgenetic alopecia
486 Hans Wolff and Kathrin Giehl 57 Alopecia areata
490 Rod Sinclair 58 Evidence-based treatment of hirsutism
498 Ulrike Blume-Peytavi and Natalie Garcia-Bartels 59 Focal hyperhidrosis
504 Kave Shams and Berthold Rzany 60 Dermal fillers
512 Stephanie Ogden and Tamara Griffiths 61 Reducing mimic wrinkles and folds with botulinum toxin A
516 Berthold Rzany SECTION 6: Other important skin disorders Michael Bigby
editor 62 Cutaneous lupus erythematosus
523 Susan Jessop and David Whitelaw 63 Dermatomyositis
531 Ruth Ann Vleugels
David F. Fiorentino
and Jeffrey P. Callen 64 Acquired subepidermal bullous diseases
545 Gudula Kirtschig
Vanessa Venning
Nonhlanhla P. Khumalo
and Fenella Wojnarowska 65 Pemphigus
552 Linda K. Martin
Brian R. Sperber
Dedee F. Murrell
and Victoria P. Werth 66 Cutaneous sarcoidosis
561 Misha Rosenbach and Joseph C. English III 67 Erythema multiforme
575 Pierre-Dominique Ghislain and Jean-Claude Roujeau 68 Stevens-Johnson syndrome and toxic epidermal necrolysis
578 Jean-Claude Roujeau
Pierre-Dominique Ghislain
and Laurence Valleyrie-Allanore 69 Polymorphic light eruption
586 Robert S. Dawe 70 Infantile hemangiomas
590 Hossain Shahidullah 71 Pruritus
595 Elke Weisshaar and Gil Yosipovitch 72 Vulval lichen sclerosus
erosive lichen planus
and vulvodynia
615 Rosalind C. Simpson
Ruth Murphy
and David Nunns 73 Venous ulcers
624 Jonathan Kantor
David J. Margolis
and Douglas J. Pugliese 74 Other skin diseases for which trials exist
632 Sinead Langan and Hywel C. Williams PART IV: The future of evidence-based dermatology Luigi Naldi
editor 75 Where do we go from here?
637 Hywel C. Williams Subject Index
644
Contributors
viii Foreword
xii Preface
xiv About the companion website
xv PART I: The concept of evidence-based dermatology Andrew Herxheimer
editor 1 The field and its boundaries
3 Luigi Naldi 2 The rationale for evidence-based dermatology
7 Hywel C. Williams and Michael Bigby 3 The role of patient and public involvement in evidence-based dermatology
12 Carron Layfield
Amanda Roberts
Jason Simons
Colette O'Sullivan
Anjna Rani
and Kim Thomas 4 The Cochrane Skin Group
17 Finola Delamere
Liz Doney
Laura Prescott
and Shirley Manknell PART II: The critical appraisal toolbox Michael Bigby
editor 5 Formulating well-built clinical questions
25 Michael Bigby and Berthold Rzany 6 Finding the best evidence
27 Michael Bigby and Rosamaria Corona 7 The hierarchy of evidence
30 Michael Bigby 8 Appraising systematic reviews and meta-analyses
33 Michael Bigby and Hywel C. Williams 9 How to critically appraise a randomized controlled trial
39 Hywel C. Williams 10 Assessing and explaining the evidence on harms of medical interventions
46 Luigi Naldi 11 How to evaluate diagnostic tests
50 Joerg Albrecht and Michael Bigby 12 What makes a good case series?
54 Joerg Albrecht and Michael Bigby 13 What makes a good prevalence survey?
58 Hywel C. Williams 14 Critical appraisal of pharmacoeconomic studies
62 Rajini K. Murthy
Laura K. DeLong
and Suephy C. Chen 15 Comparative effectiveness research: what it is and how to assess its quality
66 Junko Takeshita and Joel M. Gelfand 16 Outcome measures
71 Alain Dupuy
Emilie Sbidian
and Sylvie Bastuji-Garin 17 Where does qualitative research fit into evidence-based dermatology?
75 Ray Jobling and Luigi Naldi 18 Applying the evidence back to the patient
79 Hywel C. Williams PART III: The evidence SECTION 1: Common inflammatory skin diseases Luigi Naldi
editor 19 Acne vulgaris
87 Michael Romano and Robert P. Dellavalle 20 Papulopustular rosacea
106 Alfredo Rebora and Francesco Drago 21 Perioral dermatitis
112 Vincenzo Bettoli
Stefania Zauli
and Annarosa Virgili 22 Hand eczema
117 Wietske A. Christoffers
Marie-Louise Anna Schuttelaar
and Pieter-Jan Coenraads 23 The primary prevention of atopic dermatitis
127 Joanne R. Chalmers
Sam F. Bremmer
and Eric L. Simpson 24 Atopic eczema
136 Kim Thomas
Carolyn Charman
Helen Nankervis
Jane Ravenscroft
and Hywel C. Williams 25 Seborrheic dermatitis
169 Mauro Picardo and Norma Cameli 26 Treatment of psoriasis
175 Alexander Nast
Phyllis Spuls
and Tamar Nijsten 27 Lichen planus
200 Laurence Le Cleach and Olivier Chosidow 28 Acute urticaria
206 Torsten Schafer 29 Chronic urticaria
210 Karsten Weller and Marcus Maurer SECTION 2: Skin cancer
moles
and actinic keratoses Robert Dellavalle
editor 30 Primary prevention of skin cancer
223 Monika Janda and Adele C. Green 31 Treatment of cutaneous melanoma
231 Mary Ann N. Johnson and April W. Armstrong 32 Treatment of squamous cell carcinoma
241 Louise Lansbury
William Perkins
and Fiona Bath-Hextall 33 Basal cell carcinoma
250 Fiona Bath-Hextall and William Perkins 34 Primary cutaneous T-cell lymphoma
264 Fiona Child and Sean Whittaker 35 Actinic keratosis and Bowen's disease
283 Sasha N. Jenkins
Maren Speck
and Suephy C. Chen 36 Kaposi sarcoma
303 Whitney A. High 37 Melanocytic nevi
313 Varun Shahi and Jerry D. Brewer SECTION 3: Infective skin diseases
exanthems
and infestations Masutaka Furue and Yuping Ran
editors 38 Local treatments for cutaneous warts
320 Juping Chen and Yan Wu 39 Molluscum contagiosum
329 Minh L. Lam 40 Impetigo
337 Sander Koning
Renske van der Sande
Lisette W.A. van Suijlekom-Smit
and Johannes C. van der Wouden 41 Athlete's foot
341 Inajara Rotta
Michel F. Otuki
and Cassyano J. Correr 42 Pityriasis versicolor
345 Nancy Habib and Michael Bigby 43 Onychomycosis
349 Aditya K. Gupta
Elizabeth A. Cooper
Maryse Paquet
and Fiona Simpson 44 Tinea capitis
364 Urba Gonzalez 45 Deep fungal infections
371 Roderick J. Hay 46 Streptococcal cellulitis/erysipelas of the lower leg
378 Vinod E. Nambudiri and Michael Bigby 47 Exanthematic reactions
388 Sandra R. Knowles and Neil H. Shear 48 Herpes simplex
396 Vera Mahler 49 Leprosy
407 Saumya Panda 50 Cutaneous leishmaniasis
421 Urba Gonzalez
Armando Ruiz-Baques
and Jorge Alvar 51 Scabies
432 Ian F. Burgess 52 Head lice
441 Ian F. Burgess and Ciara S. Casey 53 Insect bites and stings
451 Belen Lardizabal Dofitas SECTION 4: Disorders of pigmentation Hywel C. Williams
editor 54 Vitiligo
464 Juan Jorge Manriquez and Sergio M. Niklitschek 55 Melasma
470 Asad Salim
Ratna Rajaratnam
and Eva Soos Domanne SECTION 5: Common ailments with significant cosmetic impact Berthold Rzany
editor 56 Male and female androgenetic alopecia
486 Hans Wolff and Kathrin Giehl 57 Alopecia areata
490 Rod Sinclair 58 Evidence-based treatment of hirsutism
498 Ulrike Blume-Peytavi and Natalie Garcia-Bartels 59 Focal hyperhidrosis
504 Kave Shams and Berthold Rzany 60 Dermal fillers
512 Stephanie Ogden and Tamara Griffiths 61 Reducing mimic wrinkles and folds with botulinum toxin A
516 Berthold Rzany SECTION 6: Other important skin disorders Michael Bigby
editor 62 Cutaneous lupus erythematosus
523 Susan Jessop and David Whitelaw 63 Dermatomyositis
531 Ruth Ann Vleugels
David F. Fiorentino
and Jeffrey P. Callen 64 Acquired subepidermal bullous diseases
545 Gudula Kirtschig
Vanessa Venning
Nonhlanhla P. Khumalo
and Fenella Wojnarowska 65 Pemphigus
552 Linda K. Martin
Brian R. Sperber
Dedee F. Murrell
and Victoria P. Werth 66 Cutaneous sarcoidosis
561 Misha Rosenbach and Joseph C. English III 67 Erythema multiforme
575 Pierre-Dominique Ghislain and Jean-Claude Roujeau 68 Stevens-Johnson syndrome and toxic epidermal necrolysis
578 Jean-Claude Roujeau
Pierre-Dominique Ghislain
and Laurence Valleyrie-Allanore 69 Polymorphic light eruption
586 Robert S. Dawe 70 Infantile hemangiomas
590 Hossain Shahidullah 71 Pruritus
595 Elke Weisshaar and Gil Yosipovitch 72 Vulval lichen sclerosus
erosive lichen planus
and vulvodynia
615 Rosalind C. Simpson
Ruth Murphy
and David Nunns 73 Venous ulcers
624 Jonathan Kantor
David J. Margolis
and Douglas J. Pugliese 74 Other skin diseases for which trials exist
632 Sinead Langan and Hywel C. Williams PART IV: The future of evidence-based dermatology Luigi Naldi
editor 75 Where do we go from here?
637 Hywel C. Williams Subject Index
644
viii Foreword
xii Preface
xiv About the companion website
xv PART I: The concept of evidence-based dermatology Andrew Herxheimer
editor 1 The field and its boundaries
3 Luigi Naldi 2 The rationale for evidence-based dermatology
7 Hywel C. Williams and Michael Bigby 3 The role of patient and public involvement in evidence-based dermatology
12 Carron Layfield
Amanda Roberts
Jason Simons
Colette O'Sullivan
Anjna Rani
and Kim Thomas 4 The Cochrane Skin Group
17 Finola Delamere
Liz Doney
Laura Prescott
and Shirley Manknell PART II: The critical appraisal toolbox Michael Bigby
editor 5 Formulating well-built clinical questions
25 Michael Bigby and Berthold Rzany 6 Finding the best evidence
27 Michael Bigby and Rosamaria Corona 7 The hierarchy of evidence
30 Michael Bigby 8 Appraising systematic reviews and meta-analyses
33 Michael Bigby and Hywel C. Williams 9 How to critically appraise a randomized controlled trial
39 Hywel C. Williams 10 Assessing and explaining the evidence on harms of medical interventions
46 Luigi Naldi 11 How to evaluate diagnostic tests
50 Joerg Albrecht and Michael Bigby 12 What makes a good case series?
54 Joerg Albrecht and Michael Bigby 13 What makes a good prevalence survey?
58 Hywel C. Williams 14 Critical appraisal of pharmacoeconomic studies
62 Rajini K. Murthy
Laura K. DeLong
and Suephy C. Chen 15 Comparative effectiveness research: what it is and how to assess its quality
66 Junko Takeshita and Joel M. Gelfand 16 Outcome measures
71 Alain Dupuy
Emilie Sbidian
and Sylvie Bastuji-Garin 17 Where does qualitative research fit into evidence-based dermatology?
75 Ray Jobling and Luigi Naldi 18 Applying the evidence back to the patient
79 Hywel C. Williams PART III: The evidence SECTION 1: Common inflammatory skin diseases Luigi Naldi
editor 19 Acne vulgaris
87 Michael Romano and Robert P. Dellavalle 20 Papulopustular rosacea
106 Alfredo Rebora and Francesco Drago 21 Perioral dermatitis
112 Vincenzo Bettoli
Stefania Zauli
and Annarosa Virgili 22 Hand eczema
117 Wietske A. Christoffers
Marie-Louise Anna Schuttelaar
and Pieter-Jan Coenraads 23 The primary prevention of atopic dermatitis
127 Joanne R. Chalmers
Sam F. Bremmer
and Eric L. Simpson 24 Atopic eczema
136 Kim Thomas
Carolyn Charman
Helen Nankervis
Jane Ravenscroft
and Hywel C. Williams 25 Seborrheic dermatitis
169 Mauro Picardo and Norma Cameli 26 Treatment of psoriasis
175 Alexander Nast
Phyllis Spuls
and Tamar Nijsten 27 Lichen planus
200 Laurence Le Cleach and Olivier Chosidow 28 Acute urticaria
206 Torsten Schafer 29 Chronic urticaria
210 Karsten Weller and Marcus Maurer SECTION 2: Skin cancer
moles
and actinic keratoses Robert Dellavalle
editor 30 Primary prevention of skin cancer
223 Monika Janda and Adele C. Green 31 Treatment of cutaneous melanoma
231 Mary Ann N. Johnson and April W. Armstrong 32 Treatment of squamous cell carcinoma
241 Louise Lansbury
William Perkins
and Fiona Bath-Hextall 33 Basal cell carcinoma
250 Fiona Bath-Hextall and William Perkins 34 Primary cutaneous T-cell lymphoma
264 Fiona Child and Sean Whittaker 35 Actinic keratosis and Bowen's disease
283 Sasha N. Jenkins
Maren Speck
and Suephy C. Chen 36 Kaposi sarcoma
303 Whitney A. High 37 Melanocytic nevi
313 Varun Shahi and Jerry D. Brewer SECTION 3: Infective skin diseases
exanthems
and infestations Masutaka Furue and Yuping Ran
editors 38 Local treatments for cutaneous warts
320 Juping Chen and Yan Wu 39 Molluscum contagiosum
329 Minh L. Lam 40 Impetigo
337 Sander Koning
Renske van der Sande
Lisette W.A. van Suijlekom-Smit
and Johannes C. van der Wouden 41 Athlete's foot
341 Inajara Rotta
Michel F. Otuki
and Cassyano J. Correr 42 Pityriasis versicolor
345 Nancy Habib and Michael Bigby 43 Onychomycosis
349 Aditya K. Gupta
Elizabeth A. Cooper
Maryse Paquet
and Fiona Simpson 44 Tinea capitis
364 Urba Gonzalez 45 Deep fungal infections
371 Roderick J. Hay 46 Streptococcal cellulitis/erysipelas of the lower leg
378 Vinod E. Nambudiri and Michael Bigby 47 Exanthematic reactions
388 Sandra R. Knowles and Neil H. Shear 48 Herpes simplex
396 Vera Mahler 49 Leprosy
407 Saumya Panda 50 Cutaneous leishmaniasis
421 Urba Gonzalez
Armando Ruiz-Baques
and Jorge Alvar 51 Scabies
432 Ian F. Burgess 52 Head lice
441 Ian F. Burgess and Ciara S. Casey 53 Insect bites and stings
451 Belen Lardizabal Dofitas SECTION 4: Disorders of pigmentation Hywel C. Williams
editor 54 Vitiligo
464 Juan Jorge Manriquez and Sergio M. Niklitschek 55 Melasma
470 Asad Salim
Ratna Rajaratnam
and Eva Soos Domanne SECTION 5: Common ailments with significant cosmetic impact Berthold Rzany
editor 56 Male and female androgenetic alopecia
486 Hans Wolff and Kathrin Giehl 57 Alopecia areata
490 Rod Sinclair 58 Evidence-based treatment of hirsutism
498 Ulrike Blume-Peytavi and Natalie Garcia-Bartels 59 Focal hyperhidrosis
504 Kave Shams and Berthold Rzany 60 Dermal fillers
512 Stephanie Ogden and Tamara Griffiths 61 Reducing mimic wrinkles and folds with botulinum toxin A
516 Berthold Rzany SECTION 6: Other important skin disorders Michael Bigby
editor 62 Cutaneous lupus erythematosus
523 Susan Jessop and David Whitelaw 63 Dermatomyositis
531 Ruth Ann Vleugels
David F. Fiorentino
and Jeffrey P. Callen 64 Acquired subepidermal bullous diseases
545 Gudula Kirtschig
Vanessa Venning
Nonhlanhla P. Khumalo
and Fenella Wojnarowska 65 Pemphigus
552 Linda K. Martin
Brian R. Sperber
Dedee F. Murrell
and Victoria P. Werth 66 Cutaneous sarcoidosis
561 Misha Rosenbach and Joseph C. English III 67 Erythema multiforme
575 Pierre-Dominique Ghislain and Jean-Claude Roujeau 68 Stevens-Johnson syndrome and toxic epidermal necrolysis
578 Jean-Claude Roujeau
Pierre-Dominique Ghislain
and Laurence Valleyrie-Allanore 69 Polymorphic light eruption
586 Robert S. Dawe 70 Infantile hemangiomas
590 Hossain Shahidullah 71 Pruritus
595 Elke Weisshaar and Gil Yosipovitch 72 Vulval lichen sclerosus
erosive lichen planus
and vulvodynia
615 Rosalind C. Simpson
Ruth Murphy
and David Nunns 73 Venous ulcers
624 Jonathan Kantor
David J. Margolis
and Douglas J. Pugliese 74 Other skin diseases for which trials exist
632 Sinead Langan and Hywel C. Williams PART IV: The future of evidence-based dermatology Luigi Naldi
editor 75 Where do we go from here?
637 Hywel C. Williams Subject Index
644