Saliha Alyar, Ümmühan Özdemir Özmen, Hamit Alyar

Environmentally-Friendly Sulfonyl Hydrazones Via One-Pot Synthesis

METHOD Sinthesis of New Alkyl Sulfonyl Hydrazones Via One-Pot and Computational Studies with DFT/B3LYP Method

• Broschiertes Buch

Produktbeschreibung

Alkyl Sulfonyl hydrazones were synthesized by onepot reaction using hydrazine hydrate, alkyl sulfonyl chlorides, and 4-hydroxy benzaldehyde under mild, inexpensive and environmentally safe conditions. In addition, these sulfonyl hydrazone syntheses provide an excellent perspective for sustainability in the production of new drug candidates. In this study, A series 4(E)-N'-(4-hydroxybenzylidene) ethanesulfonohydrazide (L1), (E)-N'-(4-hydroxybenzylidene) propane-1-sulfonohydrazide (L2), and (E)-N'-(4-hydroxybenzylidene) butane-1-sulfonohydrazide (L3) compounds were synthesized via one-pot. The synthesized compounds were characterized by FT-IR, ESI-Mass and H-NMR spectroscopy to confirm the chemical structures of synthesized compounds. The purity of all synthesized compounds were veriied using pre-coated TLC(MERCK) plates using hexane/ethyl acetate (1:1) solvent system. 1H shielding tensors for L1, L2 and L3 were calculated with GIAO/DFT/B3LYP/6-311++G(d,p) methods in DMSO. The vibrational band assignments and different chemical properties were performed at B3LYP/6-311++G(d,p) theory level.

Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Seitenzahl: 72
• Erscheinungstermin: 10. August 2020
• Englisch
• Abmessung: 220mm x 150mm x 5mm
• Gewicht: 125g
• ISBN-13: 9786202786522
• ISBN-10: 6202786523
• Artikelnr.: 60482599

Autorenporträt

Saliha Alyar wurde in Erzincan, Türkei, geboren. Im Jahr 2000 erwarb sie ihren B.A. an der Gazi Universität. Bis 2009 arbeitete sie als wissenschaftliche Mitarbeiterin an der Gazi-Universität. Im Jahr 2009 begann sie als Assistenzprofessorin an der Çank¿r¿ Karatekin Universität zu arbeiten. Sie wurde Prof. Dr. Sie hat zwei Kinder.