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Radiation treatment is an integral part of the oral cancer therapy. It is required either as a prime mode of treatment, pre-surgically /post-surgically, as a part of radio chemotherapy, or as palliative therapy. The key objective of radiotherapy is to pursue control of the tumor locally with minimal harm to the surrounding vital organs. This books gives an updated over view of various types of radiation treatment, adverse effects of radiation treatment on dentition and its management options.