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The book attempt to give the information on the use of CDK4 and AP-1 antisense oligo's to inhibit the proliferation of A549 and MCF-7 cells and also use of various modified antisense oligös (ASO) has been demonstrated. Effect of ASO on cell cycle regulation and apoptosis has been documented well. This book may help the reader to understand the use of specific ASO to inhibit the particular gene expression in cell based model. The important method such as Transfection, designing of ASO, qPCR etc have been discussed thoroughly.

Produktbeschreibung
The book attempt to give the information on the use of CDK4 and AP-1 antisense oligo's to inhibit the proliferation of A549 and MCF-7 cells and also use of various modified antisense oligös (ASO) has been demonstrated. Effect of ASO on cell cycle regulation and apoptosis has been documented well. This book may help the reader to understand the use of specific ASO to inhibit the particular gene expression in cell based model. The important method such as Transfection, designing of ASO, qPCR etc have been discussed thoroughly.
Autorenporträt
Dr.Babu R Lamani, Assistant Professor, Dept. of Bioinformatics and Biotechnology, Akkamahadevi women's University, Vijayapur,Karnataka, India 586108, Dr.Babu has ample of experience in molecular biology and systems biology. Published several research paper on molecular signalling pathway.