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Diabetes Mellitus has emerged as a global health hazard having tremendous socio-economic impact to the individual as well as society as a whole. Diabetes is one of the most common non-communicable diseases. It is one of the leading causes of death in most high-income countries and has assumed an epidemic in many developing countries. The incidence of this disease is increasing day by day due to change of dietary habits, socio-economic status, stress and sedentary life style. According to International Diabetic Federation, in the year 2014, worldwide 387 million people were afflicted with diabetes. Medical professionals have realized that attempts to control the blood sugar level by various OHA, insulin etc. is not enough to control this epidemic but a holistic approach preferably herbal medicine is required to be adopted to managed this menace. This book is an attempt to provide a handy knowledge about Ayurvedic concepts of Diabetes mellitus with special reference to a clinical study of Lagerstroemia speciosa as a hypoglycemic agent. Also described current diagnostic procedures, clinical features and management of the disease along with co-relation with Ayurvedic Concept.