Dehydroacetic Acid and Its Derivatives: Useful Synthons in Organic Synthesis outlines the use of DHA and its derivatives for the synthesis of pharmacologically active heterocyclic compounds. Beginning with an introduction to the chemistry and reactivity of Dehydroacetic Acid, the book goes on to outline the key ring transformation reactions of DHA. The synthesis of various derivatives is then discussed, before a wide range of metal complexes of DHA are explored in detail. The book then concludes with a review of DHA's biological importance and its impressive range of pharmacological…mehr
Dehydroacetic Acid and Its Derivatives: Useful Synthons in Organic Synthesis outlines the use of DHA and its derivatives for the synthesis of pharmacologically active heterocyclic compounds. Beginning with an introduction to the chemistry and reactivity of Dehydroacetic Acid, the book goes on to outline the key ring transformation reactions of DHA. The synthesis of various derivatives is then discussed, before a wide range of metal complexes of DHA are explored in detail. The book then concludes with a review of DHA's biological importance and its impressive range of pharmacological activities, including anti-cancer, anti-bacterial, anti-fungal and analgesic properties.
For those researching the synthesis of bioactive heterocyclic compounds, this book is a valuable guide on the fundamental knowledge needed to facilitate and enhance the successful synthesis of lead molecules.
Dr. Santhosh Penta completed his PhD in the field of synthetic organic and heterocyclic chemistry from NIT Warangal with postdoctoral experience with Prof. P. K. Panda, University of Hyderabad, Central University, Hyderabad. Dr. Penta has expertise in the design, synthesis, and, characterization of novel biologically potent nitrogen and sulfur heterocyclic compounds / novel chemical entities by using different methodologies and strategies. Currently during his tenure at NIT-Raipur, he has initiated the research work in multidisciplinary research programs including organic synthesis; and medicinal, combinatorial, and green chemistry, and started to study the biological activity. He is a lifetime member of scientific bodies like the Indian Council of Chemists, The Indian Science Congress Association, Materials Research Society of India, and Indian Chemical Society. Presently, three research scholars are working under his guidance for their PhD.
Inhaltsangabe
1. Introduction 2. Ring Transformations in Dehydroacetic Acid 3. Synthesis of Different Heterocyclic Compounds by Using DHA 4. Dehydroacetic Acid-Metal Complexes 5. Various Biological Activities of DHA Derivatives
1. Introduction 2. Ring Transformations in Dehydroacetic Acid 3. Synthesis of Different Heterocyclic Compounds by Using DHA 4. Dehydroacetic Acid-Metal Complexes 5. Various Biological Activities of DHA Derivatives
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