Data Analysis for Fluorescence Microscopy
Teodor Boyadzhiev
Broschiertes Buch

Data Analysis for Fluorescence Microscopy

Optimising Measurements of Epidermal Growth Factor Receptor Oligomers in Cells Using Machine Learning Algorithms

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The epidermal growth factor receptor (EGFR) is a cell surface receptor, which controls cell growth and division. Mutations affecting the receptor expression could lead to cancer. Analysis of EGFR interactions with living cells requires measuring separations between 5 and 60nm. The separations are calculated by analysing time-series of diffraction limited spots, generated by labelled EGFRs. Finding such time-series manually is time consuming and non-reproducible. This project uses machine learning algorithms in combination with understanding of the data collection process and analysis requireme...