Current Concepts in Drug Metabolism and Toxicology

Volume 63
Herausgegeben:Hawksworth, Gabrielle M.

• Gebundenes Buch

Produktbeschreibung

This new volume of Advances in Pharmacology explores the current concepts in drug metabolism and toxicology. Chapters cover the Keap1-Nrf2 cell defense pathway, animal models of drug-induced idiosyncratic toxicity and the use of human embryonic and induced pluripotent stem cells for modeling metabolism and toxicity. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike.

Produktdetails

• Advances in Pharmacology Volume 63
• Verlag: Academic Press / Elsevier Science & Technology
• Artikelnr. des Verlages: C2011-0-04514-3
• Seitenzahl: 304
• Erscheinungstermin: 12. Juni 2012
• Englisch
• Abmessung: 17mm x 152mm x 229mm
• Gewicht: 540g
• ISBN-13: 9780123983398
• ISBN-10: 0123983398
• Artikelnr.: 35940301

Inhaltsangabe

1. Membrane Transporters in Drug Development
2. The Keap1-Nrf2 Cell Defence Pathway - A Promising Therapeutic Target?
3. Animal Models of Idiosyncratic Drug Reactions
4. Genetic Polymorphisms Affecting Drug Metabolism: Recent Advances and Clinical Aspects
5. Arylamine N-Acetyltransferases - from Drug Metabolism and Pharmacogenetics to Identification of Novel Targets for Pharmacological Intervention
6. Human Pluripotent Stem Cells for Modelling Toxicity
7. Disposition of Biologics