Patricio O'Donnell (ed.)

Cortical Deficits in Schizophrenia

From Genes to Function
Herausgegeben:O'Donnell, Patricio

• Gebundenes Buch

Produktbeschreibung

This hugely important text aims to illuminate one of the most difficult areas of study in psychiatric medicine - the basis for schizophrenia in human DNA. The genetics of schizophrenia have been elusive for decades. Lately, however, a complex set of genes and gene variations that confer predisposition to schizophrenia have been identified. The challenge is to understand the biology of the genes and find out how they exert their influence. Here is all the latest research.

Produktdetails

• Verlag: Springer / Springer US / Springer, Berlin
• Artikelnr. des Verlages: 11737940
• 2008
• Seitenzahl: 256
• Erscheinungstermin: 13. November 2007
• Englisch
• Abmessung: 241mm x 160mm x 19mm
• Gewicht: 553g
• ISBN-13: 9780387743509
• ISBN-10: 0387743502
• Artikelnr.: 23072795

Inhaltsangabe

Schizophrenia Genes: Searching for Common Features, Functions, and Mechanisms.- Towards a Molecular Classification of Illness: Effects of Schizophrenia Susceptibility Loci on Clinical Symptoms and Cognitive Function.- Homer: A Genetic Factor in Schizophrenia?.- Neuregulin-erbB Signaling and the Pathogenesis of Schizophrenia.- Nicotinic Cholinergic Cortical Dysfunction in Schizophrenia.- A Role for Glutamate Receptors, Transporters, and Interacting Proteins in Cortical Dysfunction in Schizophrenia.- Cortical Circuit Dysfunction in the NMDA Receptor Hypofunction Model for the Psychosis of Schizophrenia.- Alterations in Hippocampal Function in Schizophrenia: its Genetic Associations and Systems Implications.- Identifying Novel Target Genes in Psychotic Disorder Network Association Analyses.- Alterations in Cortical GABA Neurotransmission in Schizophrenia: Causes and Consequences.- Increased Cortical Excitability as a Critical Element in Schizophrenia Pathophysiology.

Rezensionen

From the reviews:

"Cortical Deficits in Schizophrenia: From Genes to Function is an important contribution to the literature on schizophrenic syndrome analysis. It also can serve as an excellent model of productive interdisciplinary collaboration. Clinical as well as basic scientific specialists from a very wide variety of disciplines who share a common interest in schizophrenic syndrome analysis will find much new information in this work that is insightful, original, and exceptionally well integrated." (James A. Moses, PsycCRITIQUES, Vol. 34 (3), August, 2008)