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This book outlines the fundamental concepts and models of pharmacokinetics (PK) from a mathematical perspective based on clinically relevant parameters. It covers the analysis of PK data, discusses several physiological aspects to help understand the concepts, and explains processes using real-life data from pharmaceuticals. In addition, the author looks at the relationship between drug concentration and effect, known as PK/pharmacodynamics (PD) modeling. This book will enable readers to thoroughly grasp the computational factors of PK modeling.