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This book details the manifestations, diagnosis and treatment of immune-related disease in the dog and cat. It is illustrated throughout in full-color to show and explain to the reader as clearly as possible the complicated principles of disease and immunodiagnostic tests, supported by clinical cases, gross and histopathology, cytology, hematology, immunohistochemistry and other immunological tests. This fully updated Second Edition incorporates recent changes in focus and technique in the field. There is an additional chapter on respiratory and cardiac disease, and -- given the continued focus of companion animal practitioners on vaccine-related issues -- a new chapter devoted entirely to the subject of vaccinology.This text includes approximately 200 new photographic images, an updated list of recommendations for further reading, and an extensive glossary of terms.