Andere Kunden interessierten sich auch für
![Nuclear Import and Export in Plants and Animals]( "Nuclear Import and Export in Plants and Animals")
Nuclear Import and Export in Plants and Animals116,99 €![The protein factors of tRNA import into yeast mitochondria]( "The protein factors of tRNA import into yeast mitochondria")
The protein factors of tRNA import into yeast mitochondria32,99 €![Vitamin B12]( "Vitamin B12")
Vitamin B1222,99 €![Regulation of nuclear import of LIM-Kinase 2 in endothelial cells]( "Regulation of nuclear import of LIM-Kinase 2 in endothelial cells")
Regulation of nuclear import of LIM-Kinase 2 in endothelial cells40,99 €![Plasma free amino acids changes in HCC patients]( "Plasma free amino acids changes in HCC patients")
Plasma free amino acids changes in HCC patients36,99 €![Beer-Like Gluten-Free Beverages Fermented from Buckwheat and Quinoa]( "Beer-Like Gluten-Free Beverages Fermented from Buckwheat and Quinoa")
Beer-Like Gluten-Free Beverages Fermented from Buckwheat and Quinoa48,99 €![Chemistry of Free Radicals and Oxidative Stress-I]( "Chemistry of Free Radicals and Oxidative Stress-I")
Chemistry of Free Radicals and Oxidative Stress-I23,99 €
This book is based on experimental work performed at Aarhus University. The work was conducted to gain insight into the cellular endocytosis and export of vitamin B12. Vitamin B12 (cobalamin) is an organic molecule which functions as an essential coenzyme for two metabolic reactions in mammalians. Cellular vitamin B12 uptake is a complex process involving different binding proteins and receptors. The studies revealed that the endocytosis of transcobalamin bound to fluorescent vitamin B12 conjugate is correlated with cell growth in fast dividing cancer cells and the uptake of free vitamin B12 was negliable at low as well as high cell division activity. Furthermore this study provides evidenced that vitamin B12 is exported to the cellular environment as a free molecule and the binding to a carrier protein occur subsequently to export, and a novel transporter for the cellular export of vitamin B12 was identified. In conclusion, this PhD study provides new information on the cellularvitamin B12 import and in particular export by revealed a novel transport mechanism of non-protein bound vitamin B12 and the identification of a transporter protein for this process.