Cell Signalling presents a carefully structured and accessible introduction to this intricate and rapidly growing field. A focus on common components and concepts, rather than mechanistic detail, allows the reader to gain a thorough understanding of the principles that underpin cell signalling.
Cell Signalling presents a carefully structured and accessible introduction to this intricate and rapidly growing field. A focus on common components and concepts, rather than mechanistic detail, allows the reader to gain a thorough understanding of the principles that underpin cell signalling.
John Hancock is Professor of Cell Signalling at the University of the West of England. He has had a long standing interest in cell signalling and redox biology, and tries to bring these together as much as possible in his research. In addition to Cell Signalling he has published several reviews on nitric oxide and reactive oxygen species, and most recently on hydrogen sulfide.
Inhaltsangabe
* Part 1: An overview of signalling * 1: Aspects of cellular signalling * 2: Pathways are the key to signalling * 3: A look at some of the history and techniques of cell signalling * Part 2: Components that comprise signalling pathways * 4: Extracellular signals: hormones, cytokines and growth factors * 5: Detection of extracellular signals: the role of receptors * 6: Protein phosphorylation, kinases and phosphatases * 7: Cyclic nucleotides, cyclases and G proteins * 8: Inositol phosphate metabolism and roles of membrane lipids * 9: Intracellular calcium ions: control of their concentrations and roles in signalling * 10: Reactive oxygen species, reactive nitrogen species and redox signalling * Part 3: Selected examples of signalling pathways and events * 11: Insulin and the signal transduction cascades it invokes * 12: Perception of the environment * 13: Signalling in development and for the regulation of gene expression * 14: Life, death and apoptosis * Part 4: Final thoughts * 15: Cell signalling: importance, complexity and the future
* Part 1: An overview of signalling * 1: Aspects of cellular signalling * 2: Pathways are the key to signalling * 3: A look at some of the history and techniques of cell signalling * Part 2: Components that comprise signalling pathways * 4: Extracellular signals: hormones, cytokines and growth factors * 5: Detection of extracellular signals: the role of receptors * 6: Protein phosphorylation, kinases and phosphatases * 7: Cyclic nucleotides, cyclases and G proteins * 8: Inositol phosphate metabolism and roles of membrane lipids * 9: Intracellular calcium ions: control of their concentrations and roles in signalling * 10: Reactive oxygen species, reactive nitrogen species and redox signalling * Part 3: Selected examples of signalling pathways and events * 11: Insulin and the signal transduction cascades it invokes * 12: Perception of the environment * 13: Signalling in development and for the regulation of gene expression * 14: Life, death and apoptosis * Part 4: Final thoughts * 15: Cell signalling: importance, complexity and the future
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