"The definitive reference for budding and experienced cancer epidemiologists alike." -American Journal of Epidemiology"Practitioners in epidemiology and oncology will find immense value in this." -JAMANow revised for the first time in more than a decade, this fourth edition of CANCER EPIDEMIOLOGY AND PREVENTION provides a comprehensive summary of the global patterns of cancer incidence and mortality, current understanding of the major causal determinants, and a rationale for preventive interventions. Special attention is paid to molecular epidemiologic approaches that address the wider role of…mehr
"The definitive reference for budding and experienced cancer epidemiologists alike." -American Journal of Epidemiology"Practitioners in epidemiology and oncology will find immense value in this." -JAMANow revised for the first time in more than a decade, this fourth edition of CANCER EPIDEMIOLOGY AND PREVENTION provides a comprehensive summary of the global patterns of cancer incidence and mortality, current understanding of the major causal determinants, and a rationale for preventive interventions. Special attention is paid to molecular epidemiologic approaches that address the wider role of genetic predisposition and gene-environment interactions in cancer etiology and pathogenesis. For both seasoned professionals and newer generations of students and researchers, this fourth edition of CANCER EPIDEMIOLOGY AND PREVENTION remains the authoritative reference textbook in the field ¿ a work of distinction that every lab, library, student, professional, or researcher should have close at hand.
Michael J. Thun, M.D., M.S., is Vice President Emeritus of Epidemiology and Surveillance Research at the American Cancer Society. Martha S. Linet, M.D., M.P.H., is Senior Investigator at the National Cancer Institute's Division of Cancer Epidemiology. James R. Cerhan, M.D., Ph.D., is Professor of Epidemiology, Ralph S. and Beverly Caulkins Professor of Cancer Research, and Chair of the Department of Health Sciences Research, Mayo Clinic College of Medicine. Christopher A. Haiman, Sc.D., is Professor of Preventive Medicine and Aflac Chair of Cancer Research, Keck School of Medicine, University of Southern California. David Schottenfeld, M.D., M.Sc., is John G. Searle Professor Emeritus and former Chair of the Department of Epidemiology at the University of Michigan's School of Public Health.
Inhaltsangabe
Acknowledgments Contributors Preface 1 Introduction Part I - Basic Concepts 2 Biology of Neoplasia 3 Morphological and Molecular Classification of Human Cancer 4 Genomic Landscape of Cancer - Insights for Epidemiologists 5 Genetic Epidemiology of Cancer 6 Application of Biomarkers in Cancer Epidemiology 7 Causal Inference in Cancer Epidemiology Part II - The Magnitude of Cancer 8 Patterns of Cancer Incidence, Mortality, and Survival 9 Socioeconomic Disparities in Cancer Incidence and Mortality 10 The Economic Burden of Cancer in the United States Part III - The Causes of Cancer 11 Tobacco 12 Alcohol and Cancer Risk 13 Ionizing Radiation 14 Ultraviolet Radiation 15 Electromagnetic Fields 16 Occupational Cancer 17 Air Pollution 18 Water Contaminants 19 Diet and Nutrition 20 Obesity and Body Composition 21 Physical Activity, Sedentary Behaviors, and Risk of Cancer 22 Hormones and Cancer 23 Pharmaceutical Drugs Other Than Hormones 24 Infectious Agents 25 Immunologic Factors Part IV - Cancers by Tissue of Origin 26 Nasopharyngeal Cancer 27 Cancer of the Larynx 28 Lung Cancer 29 Oral Cavity, Oropharynx, Lip, and Salivary Glands 30 Esophageal Cancer 31 Stomach Cancer 32 Cancer of the Pancreas 33 Liver Cancer 34 Biliary Tract Cancer 35 Small Intestine Cancer 36 Cancers of the Colon and Rectum 37 Anal Cancer 38 Leukemias 39 Hodgkin Lymphoma 40 The Non- Hodgkin Lymphomas 41 Multiple Myeloma 42 Bone Cancers 43 Soft Tissue Sarcoma 44 Thyroid Cancer 45 Breast Cancer 46 Ovarian Cancer 47 Endometrial Cancer 48 Cervical Cancer 49 Vulvar and Vaginal Cancers 50 Choriocarcinoma 51 Renal Cancer 52 Bladder Cancer 53 Prostate Cancer 54 Testicular Cancer 55 Penile Cancer 56 Nervous System 57 Melanoma 58 Keratinocyte Cancers 59 Childhood Cancers 60 Multiple Primary Cancers Part V - Cancer Prevention and Control 61 Framework for Understanding Cancer Prevention 62 Primary Prevention 62.1 Tobacco Control 62.2 Prevention of Obesity and Physical Inactivity 62.3 Prevention of Infection-Related Cancers 62.4 Protection from Ultraviolet Radiation 62.5 Preventive Therapy 62.6 Regulation 63 Cancer Screening
Acknowledgments Contributors Preface 1 Introduction Part I - Basic Concepts 2 Biology of Neoplasia 3 Morphological and Molecular Classification of Human Cancer 4 Genomic Landscape of Cancer - Insights for Epidemiologists 5 Genetic Epidemiology of Cancer 6 Application of Biomarkers in Cancer Epidemiology 7 Causal Inference in Cancer Epidemiology Part II - The Magnitude of Cancer 8 Patterns of Cancer Incidence, Mortality, and Survival 9 Socioeconomic Disparities in Cancer Incidence and Mortality 10 The Economic Burden of Cancer in the United States Part III - The Causes of Cancer 11 Tobacco 12 Alcohol and Cancer Risk 13 Ionizing Radiation 14 Ultraviolet Radiation 15 Electromagnetic Fields 16 Occupational Cancer 17 Air Pollution 18 Water Contaminants 19 Diet and Nutrition 20 Obesity and Body Composition 21 Physical Activity, Sedentary Behaviors, and Risk of Cancer 22 Hormones and Cancer 23 Pharmaceutical Drugs Other Than Hormones 24 Infectious Agents 25 Immunologic Factors Part IV - Cancers by Tissue of Origin 26 Nasopharyngeal Cancer 27 Cancer of the Larynx 28 Lung Cancer 29 Oral Cavity, Oropharynx, Lip, and Salivary Glands 30 Esophageal Cancer 31 Stomach Cancer 32 Cancer of the Pancreas 33 Liver Cancer 34 Biliary Tract Cancer 35 Small Intestine Cancer 36 Cancers of the Colon and Rectum 37 Anal Cancer 38 Leukemias 39 Hodgkin Lymphoma 40 The Non- Hodgkin Lymphomas 41 Multiple Myeloma 42 Bone Cancers 43 Soft Tissue Sarcoma 44 Thyroid Cancer 45 Breast Cancer 46 Ovarian Cancer 47 Endometrial Cancer 48 Cervical Cancer 49 Vulvar and Vaginal Cancers 50 Choriocarcinoma 51 Renal Cancer 52 Bladder Cancer 53 Prostate Cancer 54 Testicular Cancer 55 Penile Cancer 56 Nervous System 57 Melanoma 58 Keratinocyte Cancers 59 Childhood Cancers 60 Multiple Primary Cancers Part V - Cancer Prevention and Control 61 Framework for Understanding Cancer Prevention 62 Primary Prevention 62.1 Tobacco Control 62.2 Prevention of Obesity and Physical Inactivity 62.3 Prevention of Infection-Related Cancers 62.4 Protection from Ultraviolet Radiation 62.5 Preventive Therapy 62.6 Regulation 63 Cancer Screening
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