Biology of Aminoacyl-tRNA Synthetases

Herausgegeben:Ribas de Pouplana, Lluis; Kaguni, Laurie S.

• Gebundenes Buch

Produktbeschreibung

Biology of Aminoacyl-tRNA Synthetases, Volume 48 in The Enzymes series, highlights new advances in the field, with this new volume presenting interesting chapters on A narrative about our work on the endless frontier of editing, The puzzling evolution of aminoacyl-tRNA synthetases, Structural basis of the tRNA recognition by aminoacyl-tRNA synthetases, Catalytic strategies of aminoacyl-tRNA synthetases, Trans-editing by aminoacyl-tRNA synthetase-like editing domains, Adaptive and maladaptive mistranslation arising from aminoacyl-tRNA synthetases, Non-canonical inputs and outputs of tRNA aminoacylation, Structure and function of multi-tRNA synthetase complexes, Mitochondrial aminoacyl-tRNA synthetases, Non-canonical functions of human cytoplasmic tyrosyl-, tryptophanyl- and other aminoacyl-tRNA synthetases, and much more.

Produktdetails

• The Enzymes Volume 48
• Verlag: Academic Press / Elsevier Science & Technology
• Artikelnr. des Verlages: S1874-6047(20)X0003-5
• Englisch
• Abmessung: 23mm x 152mm x 229mm
• Gewicht: 810g
• ISBN-13: 9780128202609
• Artikelnr.: 67579542

Autorenporträt

Lluís Ribas de Pouplana is ICREA Research Professor at IRB Barcelona, SpainLaurie S. Kaguni is at Michigan State University, MI, USA

Inhaltsangabe

1. The endless frontier of tRNA synthetases



Paul Schimmel



2. The evolution of aminoacyl-tRNA synthetases: From dawn to LUCA



Lluís Ribas de Pouplana



3. Putting amino acids onto tRNAs: The aminoacyl-tRNA synthetases as catalysts



Rebecca W. Alexander and Tamara L. Hendrickson



4. Trans-editing by aminoacyl-tRNA synthetase-like editing domains



Alexandra B. Kuzmishin Nagy, Marina Bakhtina and Karin Musier-Forsyth



5. Noncanonical inputs and outputs of tRNA aminoacylation



Marine Hemmerle, Marion Wendenbaum, Guillaume Grob, Nathaniel Yakobov, Nassira Mahmoudi, Bruno Senger, Sylvain Debard, Frédéric Fischer and Hubert Dominique Becker



6. Structures and functions of multi-tRNA synthetase complexes



Myung Hee Kim and Sunghoon Kim



7. Mitochondrial aminoacyl-tRNA synthetases



Joseph Chihade



8. Non-canonical functions of human tytoplasmic tyrosyl-, tryptophanyl- and other aminoacyl- tRNA synthetases



Keisuke Wakasugi and Takumi Yokosawa



9. Aminoacyl-tRNA synthetases in cell signaling



Peng Yao and Paul L. Fox



10. Human diseases linked to cytoplasmic aminoacyl-tRNA synthetases



Lei Jiang, Julia Jones and Xiang-Lei Yang



11. Aminoacyl-tRNA synthetases as drug targets



Maria Lukarska and Andrés Palencia



12. Engineering aminoacyl-tRNA synthetases for use in synthetic biology



Natalie Krahn, Jeffery Tharp, Ana Crnkovic and Dieter Söll



13. Novel functions of cytoplasmic aminoacyl-tRNA synthetases shaping the hallmarks of cancer



Justin Wang and Xiang-Lei Yang