Small angle solution scattering is now often applied to biological problems. When applied in appropriate circumstances with carefully structured questions, the technique can provide unique information not available from other techniques. This book offers understanding of the experiments with a simple and intuitive approach to the underlying theory.
Small angle solution scattering is now often applied to biological problems. When applied in appropriate circumstances with carefully structured questions, the technique can provide unique information not available from other techniques. This book offers understanding of the experiments with a simple and intuitive approach to the underlying theory.
Eaton Lattman received a BA degree from Harvard College in Chemistry and Physics, and a PhD degree from the Johns Hopkins University in Biophysics. He went on to spend many years at Johns Hopkins, rising through the ranks to become Professor, Departmental Chair, and Dean of Research and Graduate Education. He is currently Professor of Structural Biology in the School of Medicine and Biomedical Sciences, University at Buffalo, SUNY. He has published many papers in the area of structural biology, including a number on methods development. Thomas Grant received a B.S. degree from the University at Buffalo in Mathematical Physics and a PhD from the University at Buffalo in Structural Biology. After a post-doc at the Hauptman-Woodward Institute, he became a Staff Scientist as part of the NSF Science and Technology Center known as BioXFEL through the University at Buffalo. Edward Snell is President and Chief Executive Officer at the Hauptman-Woodward Medical Research Institute in Buffalo, NY, and Bioinnovations Professor at the University of Buffalo, SUNY.
Inhaltsangabe
PART I: INTRODUCTION 1: Introduction PART II: THEORY OF SMALL ANGLE SCATTERING 2: Theoretical Background 3: Quantities directly measurable by Scattering 4: Three-Dimensional Modeling of SAXS Data PART III: PRACTICAL ASPECTS OF SMALL ANGLE SCATTERING 5: Before the beamtime 6: During the beamtime 7: Analysis after the beamtime 8: Worked Examples of Data Collection, Processing, and Analysis 9: Dealing with imperfect samples 10: SAXS Instrumentation 11: High-throughput approaches to SAXS 12: Small Angle Neutron Scattering PART IV: APPLICATIONS PAST, PRESENT, AND FUTURE 13: Examples of Biological Small Angle Scattering 14: Developments on the Horizon 15: Epilogue
PART I: INTRODUCTION 1: Introduction PART II: THEORY OF SMALL ANGLE SCATTERING 2: Theoretical Background 3: Quantities directly measurable by Scattering 4: Three-Dimensional Modeling of SAXS Data PART III: PRACTICAL ASPECTS OF SMALL ANGLE SCATTERING 5: Before the beamtime 6: During the beamtime 7: Analysis after the beamtime 8: Worked Examples of Data Collection, Processing, and Analysis 9: Dealing with imperfect samples 10: SAXS Instrumentation 11: High-throughput approaches to SAXS 12: Small Angle Neutron Scattering PART IV: APPLICATIONS PAST, PRESENT, AND FUTURE 13: Examples of Biological Small Angle Scattering 14: Developments on the Horizon 15: Epilogue
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