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Thalassemia is äMendelian autosomal recessive heritable blood disorder it¿s a group of genetically determined microcytic, hypochromic anemiäs resulting from a decrease in synthesis of one or more globin chains in the hemoglobin moleculer Beta thalassemia is a fairly common blood disorder worldwide. The parents of an affected child are obligate heterozygotes and carry a single copy of a disease-causing beta globin gene mutation. At conception, each child of heterozygotes parents has 25% chance of being affected, 50% chance of being an asymptomatic carrier, and 25% chance of being unaffected and not carrier.