Gebundenes Buch

Bayesian Methods and Ethics in a Clinical Trial Design

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How to conduct clinical trials in an ethical and scientifically responsible manner This book presents a methodology for clinical trials that produces improved health outcomes for patients while obtaining sound and unambiguous scientific data. It centers around a real-world test case--involving a treatment for hypertension after open heart surgery--and explains how to use Bayesian methods to accommodate both ethical and scientific imperatives. The book grew out of the direct involvement in the project by a diverse group of experts in medicine, statistics, philosophy, and the law. Not only do th...