Boris Draznin

Atypical Diabetes

Pathophysiology, Clinical Presentations, and Treatment Options

• Broschiertes Buch

Produktbeschreibung

Although the vast majority of diabetes cases (type 1 and type 2) are polygenic diseases, research, funded by the American Diabetes Association, has found that some forms of diabetes, distinct from type 1 or type 2 diabetes, are caused by single gene mutations. It has been estimated that these monogenic forms of diabetes account for up to five percent of all diabetes cases.

Produktdetails

• Verlag: American Diabetes Association
• Seitenzahl: 560
• Erscheinungstermin: 1. Mai 2018
• Englisch
• Abmessung: 228mm x 151mm x 35mm
• Gewicht: 833g
• ISBN-13: 9781580406666
• ISBN-10: 1580406661
• Artikelnr.: 49460803

Autorenporträt

Boris Draznin, MD, PhD, is the Celeste and Jack Grynberg Professor of Medicine and a Director of the Adult Diabetes Program at the University of Colorado School of Medicine. Dr. Draznin is a member of the American Society of Clinical Investigation, Association of American Physicians, American Diabetes Association, American Association of Clinical Endocrinologists, and the Endocrine Society. Dr. Draznin served as Chair, Professional Section Advisory Panel of the American Diabetes Association, and President of the Western Association pf Physicians. He has published over 150 scientific articles and written or edited 27 books, including Diabetes Case Studies and Managing Diabetes and Hyperglycemia in the Hospital Setting, both published by the American Diabetes Association.

Inhaltsangabe

1. Table of Contents 2. Preface xiii 3. Introduction xv 4. PART I: Monogenic Diabetes: Genetic Defects of ß-cell Development and Function 5. Chapter 1: Maturity-Onset Diabetes of the Young (MODY) and Neonatal Diabetes -- 3 R. Naylor, S.A. Greeley, D. Carmody, J.L. Hwang, M. Sanyoura, L.R. Letourneau, G.I. Bell, and L. Philipson 6. Part I Case Studies Introduction -- 37 7. Case 1: KCNJ11
DEND: Neonatal Diabetes -- 41 L. Letourneau, M. Sanyoura, L. Dickens, S.A. Greeley, R. Naylor, G.I. Bell, and L. Philipson 8. Case 2: ABCC8 Neonatal Diabetes -- 44 L. Letourneau, M. Sanyoura, L. Dickens, S.A. Greeley, R. Naylor, G.I. Bell, and L. Philipson 9. Case 3: INS
Insulin Gene Mutation in Neonatal Diabetes -- 47 L. Letourneau, M. Sanyoura, L. Dickens, S.A. Greeley, R. Naylor, GI. Bell, and L. Philipson 10. Case 4: STAT3 and Neonatal Diabetes -- 51 D.W. Hansen, J.C. Sanchez, and T.S. Hannon 11. Case 5: GATA6
Heart and Pancreas -- 55 T. Triolo and K. Simmons 12. Case 6: KCNJ11 R201C
Neonatal Diabetes -- 61 L.M. Nally and D.M. Wilson 13. Case 7: PDX1
Pancreatic Agenesis -- 67 M. Sanyoura, L. Letourneau, L. Dickens, S.A. Greeley, R. Naylor, G.I. Bell, and L. Philipson 14. Case 8: Neonatal Diabetes and Congenital Hypothyroidism: GLIS3 -- 70 M. Sanyoura, L. Letourneau, L. Dickens, S.A. Greeley, R. Naylor, G.I. Bell, and L. Philipson 15. Case 9: EIF2AK3: Wolcott-Rallison Syndrome -- 73 M. Sanyoura, L. Letourneau, L. Dickens, S.A. Greeley, R. Naylor, G.I. Bell, and L. Philipson 16. Case 10: Transient Neonatal Diabetes -- 76 E.O. Buschur and K. Dungan 17. Case 11: GCK-MODY -- 81 L. Dickens, M. Sanyoura, L. Letourneau, S.A. Greeley, R. Naylor, G.I. Bell, and L. Philipson 18. Case 12: HNF1A
MODY -- 84 L. Dickens, M. Sanyoura, L. Letourneau, S.A. Greeley, R. Naylor, G.I. Bell, and L. Philipson 19. Case 13: HNF4A
MODY -- 87 L. Dickens, M. Sanyoura, L. Letourneau, S.A. Greeley, R. Naylor, G.I. Bell, and L. Philipson 20. Case 14: MODY as a Possible Diagnosis -- 90 I. Jamil and J.L. Gilden 21. Case 15: Could This Be MODY vs. Type 2? -- 95 B.Z. Osmani, J.L. Gilden, A. Moid, and C. Harris 22. Case 16: Misclassification of MODY 3 as Type 1 -- 100 L. Song, J.N. McNulty, and I. Lingvay 23. Case 17: Wolfram Syndrome WFS1 -- 105 J. Sarhis-Avigdor and E. Cengi 24. Case 18: Mitochondrial Diabetes -- 109 C. Sullivan and S. Alexanian 25. >G Mutation -- 115 B.P. Galm, S. Sirrs, and R.O. Yeung 26. >G 120 A.L. Frederilsen and H. Beck-Nielsen 27. Case 21: Maternally Inherited Diabetes and Deafness: 23-Year Follow-Up -- 125 I. Ahmad and I.B. Hirsch 28. Case 22: Glycogen Storage Type 1A Presenting with Diabetes Mellitus Type 2 -- 130 D. Sistla, M. Korytkowski, S. Mon 29. PART II: Insulin Resistance, Genetic Defects in Insulin Action, and Diseases of Exocrine Pancreas 30. Chapter 2: Insulin Resistance: Molecular Biology and Pathophysiology -- 135 C.L. Wang and B. Draznin 31. Chapter 3: The Lipodystrophy Syndromes: Clinical Features and Treatments -- 155 M. Mattingly, A. Valencia, E. Cochran, R.J. Brown, and P. Gorden 32. Chapter 4: Diabetes in Diseases of Exocrine Pancreas -- 181 J. Abramowitz, U. Gunasekaran, X.F. Samaropoulos, A. Tumyan, and I. Lingvay 33. Part II Case Studies Introduction -- 215 34. Case 23: Type A Insulin Resistance -- 218 A. Stears and R.K. Semple 35. Case 24: Donohue Syndrome (Leprechaunism) -- 225 C. Peters and R.K. Semple 36. Case 25: Rabson-Mendelhall Syndrome -- 232 R. Williams and R.K. Semple 37. Case 26: Familial Partial Lipodystrophy II (Dunninan
s Syndrome) -- 239 P.K. Cabandugama, S.A. Brietzke, M.J. Gardner, and J. Sowers 38. Case 27: Familial Partial Lipodystrophy -- 243 K.E. Kreider and M. Feinglos 39. Case 28: Severe Insulin Resistance and Lipodystrophy -- 248 K. Mekala and J. Aloi 40. Case 29: Lipodystrophy Due to PPAR-
Gene Mutation -- 253 A. Hodes, R. Brown, E. Cochran, M. Zilbermint 41. Case 30: Congenital Generalized Lipodystrophy -- 259 H. Beck-Nielsen 42. Case 31: Pancreatogenic Diabetes Mellitus --263 N. Zherdeva and B. Mankovsky 43. Case 32: A Case of Pancreatogenic Diabetes due to Alcohol Abuse --267 B.Z. Osmani, J.L. Gilden, and A. Moid 44. Case 33: Post-Pancreatectomy Diabetes -- 273 E.D. Buras, R. Cianchandani, and J. Wyckoff 45. Case 34: Diabetes and Hemochromatosis -- 277 D. Maggi, A. Aleo, L. Briatore, C. Mazzucchelli, L. Fontana, and R. Cordera 46. Case 35: Bronze Diabetes -- 281 E. Meyerhoff 47. Case 36: Type 2 Diabetes in Liver Cirrhosis and Hepatocellular Carcinoma -- 285 S. Ravi, A. Moid, J.L. Gilden, and D. Karam 48. Case 37: Poor Glycemic Control in Insulin-Treated Diabetes Due to Anti-Insulin Antibodies -- 290 D. S. Church and R.K. Semple 49. Case 38: Cystic Fibrosis-Related Diabetes -- 296 R. Iyengar, R.Y. Gianchandani, and J. Wyckoff 50. Case 39: Pembrolizumab and Diabetic Ketoacidosis -- 300 F. Cottini and K. Dungan 51. Case 40: Glycemic Control in Patient with Multiple Chronic Complications -- 305 A. Iqbal, J.L. Gilden, B.G. Theckadeth, S. Rapaka, and D. Dai 52. Case 41: Diabetes and Exposure to Agent Orange -- 309 B.Z. Osmani, J.L. Gilden, C. Harris 53. Case 42: Pasireotride-Induced Hyperglycemia -- 313 K. Brau and A. Drincic 54. Case 43: Hemoglobin A1C vs. Fructosamine -- 318 A. Iqbal, J.L. Gilden, B.G. Theckadeth, S. Rapaka, and D. Dai 55. Part III: Endocrinopathies, Immune-Mediated Diabetes, Diabetes of Unknown Cause, and Other Genetic Syndromes Sometimes Associated with Diabetes 56. Chapter 5: Diabetes Secondary to Endocrinopathies -- 325 J. M. Silverstein, K. Sterl, J. L Cartier, P. Cruz-Bravo, C. A. Davis, S. Sadiq, and J.B McGill 57. Chapter 6. Immune-Mediated Diabetes -- 357 M.F. Salam, J.W. Hughes, and J.B. McGill 58. Chapter 7. Diabetes of Unknown Cause -- 383 Y. Azhar, C.A. Baker, and N. Rasouli 59. Chapter 8. Genetic Syndromes Associated with Diabetes -- 395 A.C.H Wood, D. Abreu, A.L. Clark, M.A. Malbas, J.E. Sprague, and J.B. McGill 60. Part III Case Studies Introduction -- 423 61. Case 44: Acromegaly and Diabetic Ketoacidosis -- 426 P. Akkireddy and A. Drincic 62. Case 45: Cushing
s Syndrome and Diabetes -- 431 K. Peicher and L. Meneghini