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Diabetes mellitus is a heterogeneous metabolic disorder characterized by the presence of hyperglycemia due to impairment of insulin secretion, defective insulin action, or both. Chronic hyperglycemia in diabetes is associated with relatively specific long-term microvascular complications affecting the eyes, kidneys, and nerves, as well as an increased risk for cardiovascular disease (CVD). Atherosclerotic cardiovascular disease (ASCVD) including acute coronary syndromes (ACSs) a history of myocardial infarction (MI), stable or unstable angina, coronary or other arterial revascularization, stroke, transient ischemic attack or peripheral arterial disease presumed to be of atherosclerotic origin is the leading cause of morbidity and mortality for individuals with diabetes and is the largest contributor to the direct and indirect costs of diabetes. Common conditions coexisting with type 2 diabetes (e.g., hypertension and dyslipidemia) are clear risk factors for ASCVD.