Eman Salah El-Shafey

Assessment of the Effect of Copper Complex on Autophagy in TNBC cells

• Broschiertes Buch

Produktbeschreibung

Autophagy is a well-maintained process by which cells recycle intracellular materials to keep up homeostasis in various cellular settings. However, autophagy is a defensive mechanism that maintains cell survival under antagonistic conditions, the induction of autophagic process may substantially lead to cell death. The conflicting role of autophagy including allowing cell survival or promoting cell death could have troublesome impact on the efficiency of chemotherapeutic agents . The, current interest in copper complexes e.g., copper (I)- originated from their expanded spectrum of activity as antimicrobial, antiviral, anti-inflammatory, antitumor agents. Copper complexes frequently targeted apoptosis as a mechanism of cell death. However, the clarification of other mechanisms involved in the anti-proliferative activity of copper (I)-complexes (autophagy) may facilitate the generation of new era of copper drug

Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Seitenzahl: 136
• Erscheinungstermin: 11. Oktober 2018
• Englisch
• Abmessung: 220mm x 150mm x 9mm
• Gewicht: 221g
• ISBN-13: 9783330017634
• ISBN-10: 3330017635
• Artikelnr.: 54497308

Autorenporträt

Sono borsisti di ricerca post dottorato, specializzazione Biochimica-Dipartimento di Chimica-Facoltà di Scienze dell'Università di Damietta. Hanno ricevuto una laurea dalla Facoltà di Scienze dell'Università di Mansoura e un master dalla Facoltà di Scienze dell'Università di Mansoura. Sono interessati alla biologia cellulare-Biochimica-Cellule staminali-Biologia molecolare