Antiulcer Activity of Bioactive Fractions of Argemone mexicana in Rats

Antiulcer Activity of Bioactive Fractions of Argemone mexicana in Rats

Antiulcer activity of bioactive rich fractions from Argemone mexicana leaf in indomethacin-induced ulcerated wister rats

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Peptic ulcer disease still remains a common gastrointestinal disease particularly in sub-Sahara Africa where the burden is high. Incidence of relapses, side effects associated with conventional drugs like ompeprazole and ranitidine for treating peptic ulcer disease and their safety are among concerned factors. This book explored the antiulcerogenic activity of Argemone mexicana leaf in indomethacin-induced ulcerogenic rats. Argemone mexicana attenuated acid-secretory parameters such as gastric acid, volume, pepsin activity, pH, and hydrogen-potassium ATPase activity which are aggressive factor...