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This issue of Primary Care: Clinics in Office Practice, guest edited by Dr. Michael Malone, is devoted to Allergy Primer for Primary Care. Articles in this issue include: Indoor and Outdoor Allergies; Food Allergies; Insect Allergy; Drug Allergy; Allergic Dermatoses; Allergic Rhinitis; Respiratory Allergic Disorders; Eosinophilic Gastrointestinal Disorders; Mastocytosis; Allergy Testing; Allergy Immunotherapy; Anaphylaxis; and Complementary and Alternative Treatment for Allergic Conditions.