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Guest editor Lena Napolitano has assembled and expert team of authors on the topic of Surgery in the ICU. Articles will focus on: Oxygen Support and Mechanical Ventilation Advances; Ventilator-associated Pneumonia - New Definitions;Optimal Strategies for Severe ARDS; Persistent Inflammation/Immunosuppression Syndrome; ABCDE Bundle in Critical Care;Renal Replacement Therapy in Acute Kidney Injury: Consensus?; Transfusion Advances in Critical Care; Severe Sepsis and Septic Shock: ProCESS; ARISE: PROMISE - What is Optimal Resuscitation?; Nutritional Support in Critical Care: What is the Evidence?; Acute Kidney Injury and Outcomes; and Tracheostomy Update: When and How?