History and Development of Nucleotide Analogues in Nucleic Acids Drugs Mechanisms of Antisense Oligonucleotides The Medicinal Chemistry of RNase H-activating Antisense Oligonucleotides Antisense Technology: Liver Targeting and Beyond for Drug Discovery Oligonucleotide-based Toll-like Receptor Antagonists and Therapeutic Applications Splicing Modulation for Therapeutics Targeting Toxic Repeats Research and Development of Oligonucleotides Targeting MicroRNAs (miRNAs) Oligonucleotide Targeting of Long Non-coding RNAs Conjugate-mediated Delivery of RNAi-based Therapeutics: Enhancing Pharmacokinetics-Pharmacodynamics Relationships of Medicinal Oligonucleotides Liver-targeted RNAi Therapeutics: Principles and Applications Advances and Challenges of RNAi-Based Anti-HIV Therapeutics Nucleic Acid Innate Immune Receptors Synthetic Agonists of Toll-like Receptors and Therapeutic Applications Prostate-specific Membrane Antigen (PSMA) Aptamers for Prostate Cancer Imaging and Therapy Aptamers and Clinical Applications CRISPR-based Technologies for Genome Engineering: Properties, Current Improvements and Applications in Medicine Therapeutic Potential of Ribozymes Large-scale Automated Synthesis of Therapeutic Oligonucleotides: A Status Update Preclinical and Clinical Drug-metabolism, Pharmacokinetics and Safety of Therapeutic Oligonucleotides Subject Index
History and Development of Nucleotide Analogues in Nucleic Acids Drugs Mechanisms of Antisense Oligonucleotides The Medicinal Chemistry of RNase H-activating Antisense Oligonucleotides Antisense Technology: Liver Targeting and Beyond for Drug Discovery Oligonucleotide-based Toll-like Receptor Antagonists and Therapeutic Applications Splicing Modulation for Therapeutics Targeting Toxic Repeats Research and Development of Oligonucleotides Targeting MicroRNAs (miRNAs) Oligonucleotide Targeting of Long Non-coding RNAs Conjugate-mediated Delivery of RNAi-based Therapeutics: Enhancing Pharmacokinetics-Pharmacodynamics Relationships of Medicinal Oligonucleotides Liver-targeted RNAi Therapeutics: Principles and Applications Advances and Challenges of RNAi-Based Anti-HIV Therapeutics Nucleic Acid Innate Immune Receptors Synthetic Agonists of Toll-like Receptors and Therapeutic Applications Prostate-specific Membrane Antigen (PSMA) Aptamers for Prostate Cancer Imaging and Therapy Aptamers and Clinical Applications CRISPR-based Technologies for Genome Engineering: Properties, Current Improvements and Applications in Medicine Therapeutic Potential of Ribozymes Large-scale Automated Synthesis of Therapeutic Oligonucleotides: A Status Update Preclinical and Clinical Drug-metabolism, Pharmacokinetics and Safety of Therapeutic Oligonucleotides Subject Index
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