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This issue of Primary Care: Clinics in Office Practice, devoted to Adolescent Medicine, is edited by Drs. William B. Shore, Francesco Leanza, and Nicole Chaisson. Articles in this issue include: Health Care Maintenance for Adolescents; Adolescent Growth and Development; Puberty; Current Concepts of Psychosocial Development; Body Image and Health: Eating Disorders and Obesity; Working with Families with Adolescents; Care for Adolescents with Developmental Delay; Sports Medicine; Sports Injuries; Teens and Technology; Care of Incarcerated Youth; Mental Illness in Adolescence; Substance Use/Abuse; Current Approach to Contraception and Pregnancy; Oral/Hormonal Contraception; Sexually Transmitted Infections; Teen Sexuality and GLBT Youth; and Bullying and Violence Prevention.