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Generalized anxiety, post-traumatic stress or existential thoughts can lead the brain to enter a "defensive" mode of consciousness far from reality where the perception of the self and the perception of the world result noticeably altered. The author makes an autobiographical journey of his history as a consequence of this disorder to describe the main symptoms of Depersonalization (DP) and Desrealization (DR) and presents a hypothesis about its nature based on a relative disconnection between rational and emotional hemispheres. The most frequent causes leading to Depersonalization (alteration of the self) and to Derealization (alteration of the perception of the world) are reviewed and the method of Santos Barrios (c) is presented as a natural treatment to return the individual to normality. The indiscriminate use of new technologies (smartphones, tablets, PCs, videogames, social networks, streaming on demand, ...) causes people avoid more and more the contact with the physical and emotional reality of the environment. This fact together with anxiety, the rush of everyday life, the concern for an uncertain future and the possible consumption of drugs constitute an explosive cocktail that is making an appearance of cases of distancing from reality.