Eglen

5-HT4 Receptors in the Brain and Periphery

Herausgegeben:Eglen, Richard M.

• Gebundenes Buch

Produktbeschreibung

This book provides a comprehensive, up-to-date review of the distribution, pharmacology and physiology of central 5-hydroxytryptamine (5-HT)4 receptors. The 5-HT receptor subtypes exhibit a unique pharmacology, distribution and function, of which the 5-HT4 receptor has been one of the most intensively studied in recent years, both from a basic research standpoint and as a target for novel therapeutics.

Produktdetails

• Biotechnology Intelligence Unit
• Verlag: Springer / Springer Berlin Heidelberg / Springer, Berlin
• Artikelnr. des Verlages: 978-3-540-64164-3
• 1998.
• Seitenzahl: 248
• Erscheinungstermin: 19. August 1998
• Englisch
• Abmessung: 241mm x 160mm x 19mm
• Gewicht: 530g
• ISBN-13: 9783540641643
• ISBN-10: 3540641645
• Artikelnr.: 26688296

Inhaltsangabe

1. Medicinal Chemistry of 5-HT4 Receptor Ligands.- 2. Molecular Biology of 5-HT4 Receptors.- 3. Localization of 5-HT4 Receptors in Vertebrate Brain and Their Potential Behavioral Roles.- 4. Central 5-HT4 Receptors: Electrophysiology.- 5. Neurochemical Consequences Following Pharmacological Manipulation of Central 5-HT4 Receptors.- 6. 5-Hydroxytryptamine and Human Heart Function: The Role of 5-HT4 Receptors.- 7. 5-HT4 Receptors in Gastrointestinal Tract.- 8. 5-HT4 Receptors in Lower Urinary Tract Tissues.- 9. The 5-HT4 Receptor in the Adrenal Gland.- 10. Therapeutic Applications of 5-HT4 Receptor Agonists and Antagonists.