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The book helps the reader to better understand cytogenetics and the intricacies of the methodology. The different methods of fluorescence in situ hybridization are discussed and the results achieved are presented. The book provides a comprehensive review of basic and applied aspects of cytogenetics and thus is of intense interest to all those interested in chromosomes and their alterations by different types of mutagens, including chemical mutagens and ionizing and nonionizing radiation, with special reference to electromagnetic fields. …mehr

Produktbeschreibung
The book helps the reader to better understand cytogenetics and the intricacies of the methodology. The different methods of fluorescence in situ hybridization are discussed and the results achieved are presented. The book provides a comprehensive review of basic and applied aspects of cytogenetics and thus is of intense interest to all those interested in chromosomes and their alterations by different types of mutagens, including chemical mutagens and ionizing and nonionizing radiation, with special reference to electromagnetic fields.
  • Produktdetails
  • Verlag: Springer, Berlin
  • Artikelnr. des Verlages: 11669876
  • 2007
  • Seitenzahl: 540
  • Erscheinungstermin: 3. Juli 2007
  • Englisch
  • Abmessung: 241mm x 160mm x 33mm
  • Gewicht: 884g
  • ISBN-13: 9783540714132
  • ISBN-10: 3540714138
  • Artikelnr.: 22708842
Autorenporträt
Both editors have a year long experience in cytogenetic research and published many papers in peer reviewed journals on different topics of cytogenetics.
Inhaltsangabe
1 Human Chromosomes: Structural and Functional Aspects.- 2 DNA Lesions Induced by Ionizing Radiation.- 3 Effects of Ultraviolet Radiation on DNA.- 4 Double Strand Break Repair Mechanisms in Mammalian Cells.- 5 Backup Pathways of Nonhomologous End Joining May Have a Dominant Role in the Formation of Chromosome Aberrations.- 6 Targeted and Non-Targeted Induction of Chromosomal Rearrangements After Exposure to Ionizing Radiation.- 7 DNA Methylation Damage: Formation, Repair and Biological Consequences.- 8 Adducts, Sister-Chromatid Exchanges and Mutations Following Benzo[a]pyrene Exposure: a Review of Quantitative Data Followed by Some Considerations Regarding Risk.- 9 Analysis of DNA Double-Strand Breaks by Means of g-H2AX Foci.- 10 Comet Assay.- 11 Origin of Chromosome Aberrations: Mechanisms.- 12 Chromatin Structure and the Formation of Chromosomal Alterations.- 13 Role of Chromatin Structure and Activity in the Induction of Chromosomal Aberrations.- 14 A Biomedical Perspective of