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This book constitutes the refereed proceedings of the First International Workshop on Computer Assisted and Robotic Endoscopy, CARE 2014, held in conjunction with MICCAI 2014, in Boston, MA, USA, in September 2014. The 12 papers presented focus on recent technical advances associated with computer vision; graphics; robotics and medical imaging; external tracking systems; medical device control systems; information processing techniques; endoscopy; planning and simulation.