Airway Smooth Muscle in Asthma and COPD (eBook, PDF)

Biology and Pharmacology
Redaktion: Chung, Kian Fan

• Format: PDF

Produktbeschreibung

In this book, leading researchers in medicine and molecular pharmacology explain the cellular mechanisms that control airway smooth muscle. The means by which these are disrupted in disease, and the pharmacologic strategies by which they may be modified are discussed and future therapeutic interventions are identified. Aimed at specialists in pulmonology, this volume provides the clinician with the most up to date information on one of the core physiological processes in airway disease, and offers insights into current and future approaches to management. * Authoritative update on key mechanisms of airway constriction in Asthma and COPD * Relates latest research to bronchodilator therapy * Multi-contributed text, co-coordinated by two of the leading authorities in the field.

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Produktdetails

• Verlag: John Wiley & Sons
• Seitenzahl: 326
• Erscheinungstermin: 2. August 2008
• Englisch
• ISBN-13: 9780470754214
• Artikelnr.: 37299074

Autorenporträt

K Fan Chung, Professor, Experimental Studies Group, Royal Brompton Campus; Editorial Board member of American Journal Respiratory Critical Care Medicine, Respirology

Inhaltsangabe

List of Contributors. 1. Biophysical basis of airway smooth muscle
contraction and hyperresponsiveness in asthma (Steven S. An and Jefferey J.
Fredberg). References. 2. Dynamics of cytoskeletal and contractile protein
organization: an emerging paradigm for airway smooth muscle contraction
(Wenwu Zhang and Susan J. Gunst). References. 3. Airway smooth muscle: role
in airway constrictor hyperresponsiveness (Melanie Brown and Julian
Solway). Acknowledgements. References. 4. Airway smooth muscle phenotypic
and functional plasticity (Andrew J. Halayko, Reinoud Gosens and Thai
Tran). References. 5. Airway smooth muscle proliferation: insights into
mechanisms regulating airway smooth muscle mass (Reynold A. Panettieri,
Jr.). References. 6. Airway smooth muscle bidirectional interactions with
extracellular matrix (Jane E. Ward and Stuart J. Hirst). Acknowledgements.
References. 7. Airway smooth muscle interaction with mast cells (Roger
Marthan, Patrick Berger, Pierre-Olivier Girodet and J. Manuel
Tunon-de-Lara). Acknowledgements. References. 8. Airway smooth muscle
synthesis of inflammatory mediators (Alison E. John, Deborah L. Clarke,
Alan J. Knox and Karl Deacon). References. 9. Airway smooth muscle in
experimental models (Anne-Marie Lauzon and James G. Martin).
Acknowledgement. References. 10. Altered properties of airway smooth muscle
in asthma (Judith Black, Janette Burgess, Brian Oliver and Lyn Moir).
References. 11. The airway smooth muscle in chronic obstructive pulmonary
disease (COPD) (Maria B. Sukkar and Kian Fan Chung). References. 12.
Glucocorticoid actions on airway smooth muscle (Ian M. Adcock, Loukia
Tsaprouni and Pank Bhavsar). Acknowledgements. References. 13.
ß2-Adrenergic receptors: effects on airway smooth muscle (Malcolm Johnson).
References. 14. Asthma treatments: effects on the airway smooth muscle
(Kian Fan Chung). Index.

Rezensionen

Aimed at specialists in pulmonology, this volume provides the clinician with the most up to date information on one of the core physiological processes in airway disease, and offers insights into current and future approaches to management. ( Doody s Reviews , March 2009)