T. Godfraind

Calcium Channel Blockers

• Gebundenes Buch

Produktbeschreibung

The main effect of calcium channel blockers is the blockade of calcium entry into cells through voltage operated calcium channels. This volume gives a comprehensive overview of the different classes of CCBs and their various effects. It covers historical development, pharmacology, clinical aspects, and perspectives. All chapters are written by Prof. T. Godfraind, a world leading expert in the field.

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Produktdetails

• Milestones in Drug Therapy
• Verlag: Birkhäuser Basel / Springer, Basel
• Artikelnr. des Verlages: 10783529
• 2004
• Seitenzahl: 280
• Erscheinungstermin: 26. März 2004
• Englisch
• Abmessung: 241mm x 160mm x 21mm
• Gewicht: 765g
• ISBN-13: 9783764364359
• ISBN-10: 3764364351
• Artikelnr.: 12352291

Autorenporträt

Théophile Godfraind, Université Catholique de Louvain, Bruxelles, Belgien

Inhaltsangabe

Preface.- Acknowledgements.- Historical perspective: from early steps on calcium research to the identification of calcium antagonist prototypes and of the signaling functions of Ca2+.- Calcium channel blockers and calcium channels.- The action of calcium antagonists onCa2+ movements in isolated vessels.- The tissue selectivity of calcium antagonists.- Acute haemodynamic effects of calcium channel blockers.- Calcium channels and regulation of vascular tone in hypertension.- Long-term effects of calcium antagonists.- Blood-pressure independent effects of calcium antagonists.- From early clinical studies to randomized controlled clinical trials.- Beyond the cardiovascular system.- Index.