1. Implementation of BEP.- 2. Scientific and technical value.- 3. Interest for the Community.- 4. The Biotechnology Action Programme.- 5. Role of the Advisory Committees.- Summary Reviews of Scientific Achievements by Research Sectors.- 1. Sector 1 : Second generation bioreactors.- 2. Sector 2.1 : Genetic engineering of virus and cellular genes important in animal husbandry.- 3. Sectors 2.2 + 3 : Genetic engineering of microorganisms important for agro-food industries.- 4. Sector 4 : Genetic engineering of plants and micro-organisms important for agriculture.- Coordination Activities.- 1. Scientific meetings.- 2. Visits to laboratories.- 3. Publications and reports.- Final Reports from the laboratories participating in the research programme.- 1. Development of second generation bioreactors (multi-enzymatic, multiphase or requiring a co-factor) for detoxification and for industrial applications including agro-food applications..- 2. Improved production, by means of biomolecular engineering methods, of substances for: - animal husbandry (particularly vaccines and hormones), - agro-food industries..- 2.1 Animal husbandry.- 2.2 Agro-food industries..- 3. Upgrading of plant products, particularly ligno-cellulose, by means of biomolecular engineering methods..- 4. Improvement, by means of genetic engineering, of plants and microorganisms which play an important role in agriculture..- 5. Development of methods for detecting contamination and for the assessment of possible risks associated with applications of biomolecular engineering in agriculture and industry..- Indexes.- 1. Index of project leaders.- 2. Index of keywords.- 3. Index of cities.- 4. Index of contract numbers.