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Leading interventional cardiologists, including Patrick Serruys, Eric Topol, David Holmes, Thomas Luscher and others provide the gold-standard reference on the treatment of restenosis (coronary artery blockage) for interventional cardiologists. Dr. Serruys, who pioneered the use of drug-eluting stents, and other pioneers in the field cover everything from non-invasive imaging, to eluting stents, to brachytherapy through to the latest molecular biology-based treatments including antisense, stem cells and gene therapy, making this an essential reference for all interventional cardiologists.…mehr

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Produktbeschreibung
Leading interventional cardiologists, including Patrick Serruys, Eric Topol, David Holmes, Thomas Luscher and others provide the gold-standard reference on the treatment of restenosis (coronary artery blockage) for interventional cardiologists. Dr. Serruys, who pioneered the use of drug-eluting stents, and other pioneers in the field cover everything from non-invasive imaging, to eluting stents, to brachytherapy through to the latest molecular biology-based treatments including antisense, stem cells and gene therapy, making this an essential reference for all interventional cardiologists. TOC:Epidemiology and Pathogenesis of Restenosis.- Clinical Presentation of Restenosis.- Pathologic Anatomy of Restenosis.- The Influence of Shear Stress on Restenosis.- Role of the Immune System in the Pathogenesis of Vascular Proliferative Disease.- Animal Restenosis Models.- From the "Ideal Model" to the "Ideal Study".- The Genomics of Restenosis.- Gene Expression Profiling and Restenosis.- Proteomics and Restenosis.- Contribution of Circulating Progenitor Cells to Vascular Repair and Lesion Formation.- Cell Cycle Regulation in Vascular Proliferative Diseases.- Arterial Remodelling.- The role of eNOS in Vascular Diseases.- The Use of Pressure Gradient Analysis in the Diagnosis of Restenosis.- The Use of Radio Isotopes in the Diagnosis of Vascular Proliferative Disease.- Magnetic resonance imaging for restenosis.- Coronary Imaging with Multislice Spiral Computed Tomography.- Pharmacotherapy of Restenosis.- Brachytherapy.- Pre-clinical Data of Eluting Stents.- Clinical Data of Eluting Stents.- Biodegradable Stents.- Vascular Gene Therapy.- Antisense and ODN Transcription Factors in the Treatment of Vascular Proliferative Disease.- Cell Cycle Approaches to the Treatment of In-stent Restenosis.- Local Gene and Cell Delivery Devices.

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  • Produktdetails
  • Verlag: Springer-Verlag GmbH
  • Erscheinungstermin: 13. November 2007
  • Englisch
  • ISBN-13: 9781597450010
  • Artikelnr.: 37342139
Autorenporträt
Henricus J. Duckers, University of Rotterdam, The Netherlands / Patrick W. Serruys, University of Rotterdam, The Netherlands / Elizabeth G. Nabel, National Institutes of Health, Bethesda, MD, USA
Inhaltsangabe
Essentials of Restenosis for the Interventional CardiologistTable of Contents:Part A. IntroductionHenricus J. DuckersCaroline ChengDennie TempelPatrick W. SerruysPart B. Pathophysiology and DiagnosisChapter:1. Epidemiology and Pathogenesis of Restenosis Randolph L. GearyAlexander W. Clowes2. Clinical Presentation of Restenosis Ganesh ManoharanGiedrius DavidaviciusWilliam Wijns3. Pathologic Anatomy of Restenosis Renu VirmaniFrank D. KolodgieAloke V. FinnHerman K. Gold4. The Influence of Shear Stress on Restenosis Attila ThuryCornelis J. Slager et al.5. Role of the Immune System in thePathogenesis of Vascular Proliferative Disease Jon D. LamanBurkhard Ludewig6. Animal Restenosis Models.From the âEURoeIdeal ModelâEUR? to the âEURoeIdeal StudyâEUR? Arturo G. TouchardRobert S. SchwartzPart C. Genetic base of restenosisChapter:7. The Genomics of Restenosis Thomas W. JohnsonKarl R. Karsch8. Gene Expression Profiling and Restenosis Dietlind ZohlnhöferFranz-Josef Neumann9. Proteomics and
Rezensionen
From the reviews:

"This is a comprehensive review of the problem of restenosis, from the basic science to clinical management. ... The audience includes interventional cardiology fellows and interventional cardiologists. The book describes the difficulties that cardiologists face trying to prevent and manage restenosis. ... Each chapter includes extensive references. This is a complete, state-of-the-art review of restenosis, covering all aspects of restenosis from pathophysiology to therapeutic management. The authors are leaders in interventional cardiology with extensive clinical experience in the field." (Adriana Maria Rosario, Doody's Review Service, December, 2007)

"A multiauthored, comprehensive compendium of virtually all aspects of the restenotic process after balloon- or stent-induced arterial injury. ... The text is written by a blueribbon panel of authors who provide an in-depth coverage of the topics. Many of the clinical chapters offer an excellent historical perspective on the problem of restenotis. ... Recommended Readership: Interventional (clinical and research) cardiologists and interventional fellows." (John F. Bresnahan, Mayo Clinic Proceedings, Vol. 83 (4), April, 2008)