Richard G. Pestell (ed.)

Prostate Cancer

Signaling Networks, Genetics, and New Treatment Strategies
Herausgegeben:Pestell, Richard G.; Nevalainen, Marja T.;Mitarbeit:Milken, M.

• Gebundenes Buch

Produktbeschreibung

Award winning authors present a comprehensive review of new perspectives in prostate cancer research and open up new directions in the clinical management of prostate cancer. In, "Prostate Cancer: Signaling Networks, Genetics, and New Treatment Strategies", the authors focus on the biology, genetics, molecular signaling networks in the disease process, and recent advances in the treatment of prostate cancer. This state-of-the-art title provides key insights into cutting edge advances in prostate cancer research, such as laparoscopic radical prostatectomy, and offers a critical evaluation and discussion of opportunities for development of novel therapies for prostate cancer. Clinical trials that have not been covered or evaluated in any other books currently available are also discussed. Invaluable to physicians and researchers, "Prostate Cancer: Signaling Networks, Genetics, and New Treatment Strategies" provides a comprehensive translational resource as well as an important source of information for prostate cancer patients.

Produktdetails

• Current Clinical Oncology
• Verlag: Humana / Humana Press / Springer, Berlin
• Artikelnr. des Verlages: 12000104, 978-1-58829-741-9
• 2008
• Seitenzahl: 472
• Erscheinungstermin: 19. März 2008
• Englisch
• Abmessung: 241mm x 160mm x 30mm
• Gewicht: 869g
• ISBN-13: 9781588297419
• ISBN-10: 1588297411
• Artikelnr.: 22708713

Inhaltsangabe

Histopathology and Molecular Biology of Prostate Atrophy.- Epigenetic Gene Silencing in Prostate Cancer.- Inherited Genetic Changes in Prostate Cancer.- Prostate Molecular Oncogenesis.- Somatic Genetic Changes in Prostate Cancer.- Androgen Receptor in Prostate Cancer Progression.- Epigenetic Modification and Acetylation of Androgen Receptor Regulate Prostate Cellular Growth.- Estrogen Receptor ? and ? in the Regulation of Normal and Malignant Prostate Epithelium.- Estrogen Action in Normal Prostate Epithelium and in Prostate Cancer.- Hypoxia-Inducible Factor 1 in the Angiogenesis of Prostate Cancer.- Signal Transduction by the Ras-MAP Kinase Pathway in Prostate Cancer Progression.- Transcription Factors STAT5 and STAT3.- Role of PI3K-Akt and PTEN in the Growth and Progression of Prostate Cancer.- New Perspectives in Prediction of Clinical Outcome of Prostate Cancer.- New Directions in Radiation Therapy of Prostate Cancer.- The Current Knowledge of Hormonal Therapy in the Treatment of Prostate Cancer.- Advances in Surgical Intervention of Prostate Cancer.- Targeted Therapy Trials for Prostate Cancer.- New Perspectives on Chemotherapy in Prostate Cancer.- Concluding Remarks.

Rezensionen

From the reviews:

"In this detailed and up-to-date book, leaders in prostate cancer research review the current knowledge of genetic pathways and major molecular aberrations involved in prostate cancer as well as the treatment of the disease. ... The figures and tables are clear and provide essential additional information. ... the editors and authors have succeeded in clearly summarizing the most important recent advances in prostate cancer research, and the book will interest urologists, medical oncologists, and prostate cancer researchers." (Joost L. Boormans, The New England Journal of Medicine, August, 2008)