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This book summarizes the most advanced technical aspects covering all steps for a thorough application of microarrays to inflammation topics - from sample generation to data analysis. In addition selected examples of successful applications of microarrays in major fields of inflammation research are presented. The book will help a researcher or clinician to plan, perform and analyze or to critically review microarray experiments related to inflammation research. …mehr

Produktbeschreibung
This book summarizes the most advanced technical aspects covering all steps for a thorough application of microarrays to inflammation topics - from sample generation to data analysis. In addition selected examples of successful applications of microarrays in major fields of inflammation research are presented. The book will help a researcher or clinician to plan, perform and analyze or to critically review microarray experiments related to inflammation research.
  • Produktdetails
  • Progress in Inflammation Research
  • Verlag: Birkhäuser / Birkhäuser Basel / Springer, Basel
  • Artikelnr. des Verlages: 11812548
  • Erscheinungstermin: 20. Oktober 2008
  • Englisch
  • Abmessung: 241mm x 170mm x 18mm
  • Gewicht: 708g
  • ISBN-13: 9783764383336
  • ISBN-10: 376438333X
  • Artikelnr.: 23114355
Inhaltsangabe
Microarray and inflammation: An introduction.- Microarray and inflammation: An introduction.- Methods and protocols for the generation of gene expression profiles in inflammation research.- Whole blood.- Separation of whole blood cells and its impact on gene expression.- Skin and skin models.- Adipose tissue.- Samples isolated by flow cytometry.- Magnetic cell sorting.- T7 based amplification protocols.- Amplification of cDNA from single or rare cells by global PCR (exponential amplification).- Selected applications of microarrays in inflammation research.- Gene expression patterns in asthma.- Gene expression profiling in neurological and neuroinflammatory diseases.- Aspects of gene expression in B cell lymphomas.- The genes behind rheumatology.- miRNA patterns in hematopoietic malignancies.- Keep it simple: microarray cross-platform comparison without statistics.- Microarrays in drug development: regulatory perspective.- Outlook.- Complementary microarray technologies.