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  • Format: PDF


Transforming Growth Factor- ß in Cancer Therapy, Vols. 1 and 2, provides a compendium of findings about the role of transforming growth factor- ß (TGF- ß) in cancer treatment and therapy. The second volume, Cancer Treatment in Therapy, is divided into three parts. The companion volume details the role of TGF- ß on basic and clinical biology.…mehr

Produktbeschreibung
Transforming Growth Factor- ß in Cancer Therapy, Vols. 1 and 2, provides a compendium of findings about the role of transforming growth factor- ß (TGF- ß) in cancer treatment and therapy. The second volume, Cancer Treatment in Therapy, is divided into three parts. The companion volume details the role of TGF- ß on basic and clinical biology.

Dieser Download kann aus rechtlichen Gründen nur mit Rechnungsadresse in A, B, BG, CY, CZ, D, DK, EW, E, FIN, F, GB, GR, HR, H, IRL, I, LT, L, LR, M, NL, PL, P, R, S, SLO, SK ausgeliefert werden.

  • Produktdetails
  • Verlag: Springer-Verlag GmbH
  • Erscheinungstermin: 01.01.2010
  • Englisch
  • ISBN-13: 9781597452939
  • Artikelnr.: 37353845
Autorenporträt
Sonia Jakowlew, National Cancer Institute, Rockville, MD, USA
Inhaltsangabe
Transforming Growth Factor-ß in Cancer Therapy Volume 2: Cancer Treatment and Therapy Sonia B. Jakowlew, Ph.D., Editor The Humana Press, Inc., Publisher TABLE OF CONTENTS In Memorium for Anita B. Roberts, PhD John M. McPherson Preface Sonia B. Jakowlew Foreward Carl-Henrick Heldin Contributors Part I. Transforming Growth Factor-ß in Developing and Advanced Cancers 1 Transforming Growth Factor-ß Signaling in Pancreas Development and Pancreatic Cancer Sushil Rane , Huei-Min Lin, Ji-Hyeon Lee, and Wan Jiao 2 Role of Transforming Growth Factor-ß (TGF-ß) in the Pathogenesis of Head and Neck Squamous Cell Carcinoma (HNSCC) Stephen M. Weber, Shi-Long Lu, Sophia Bernstein, and Xiao-Jing Wang 3 TGF-ß, Smads and Cervical Cancer Devarajan Karunagaran and Goodwin Jinesh 4 TGF-ß Signaling and Biglycan in Pancreatic Cancer Hendrik Ungefroren 5 TGF-ß Signaling in Endometrial Cancer Dagmara Piestrzeniewicz-Ulanska , David H. McGuinnes, and Grant R. Yeaman 6 TGF-ß Ligands, TGF-Ã Receptors, and Lung Cancer Guiying Wang, Rongmei Zhang, Xiaohua Hu, Jiucun Wang, Lindsey J. Leach, and Zewei Luo 7 Role of TGF-ß in Osteolytic Bone Metastases Laurent Bartholin and Thesesa A. Guise 8 Hormonal Regulation of Transforming Growth Factor-beta in Breast Cancer Miriam Buck and Cornelius Knabbe 9 TGF-ß Signaling in Esophageal Cancer Minoru Fukuchi , Hiroyuki Kato, and Hiroyuki Kuwano 10 TGF-beta and HER2/ErbB2 and Breast Cancer Progression Natasa Todorovic-Rakovic 11 TGF-beta dependent T Cell Regulation in Colitis and Colon Cancer Christoph Becker and Markus F. Neurath 12 Role of Transforming Growth Factor-beta in the Kidney - Physiology and Pathology Elena Gagliardini and Ariela Benigni 13 Perturbations of TGF-ß Signaling in Leukocytes as Driversof Leukemogenesis and Epithelial Tumorigenesis Lawrence A. Wolfraim and John J. Letterio 14 Transforming Growth Factor-ß in Brain Functions and Dysfunctions Denis Vivien , Karim Benchenane, and Carine Ali 15 Inhibition of TGF-ß Signaling in Multiple Myeloma and it's Bone Marrow Environment Hiroshi Yasui, Teru Hideshima, and Kenneth C. Anderson 16 Key Roles of Smad3 in TGF-ß Responses in the Prostate Kyung Song and David Danielpour 17 Smad Signaling in Leukemic Growth and Differentiation: Crosstalk Between Smad and Multiple Pathways Through Activation of the TGF-ß Type I Receptor Francis W. Ruscetti , Salem Akel, Maria Birchenall-Roberts, Zhouhong Cao, and Anita Roberts Part II. Transforming Growth Factor-ß in Cancer Treatment and Therapy 18 High Throughput Screening of Protein Interaction Networks in the TGFß Interactome: Understanding the Signaling Mechanisms Driving Tumor Progression Miriam Barrios-Rodiles, Alicia Viloria-Petit, Kevin R. Brown, Igor Jurisica, and Jeffrey L. Wrana 19 Tumor Suppressor and Pro-Progression Roles for TGF-ß in Breast Cancer Ethan Kohn and Binwu Tang 20 Tumor Suppressors p53 and TGF-ß Converge to Regulate the Alpha-fetoprotein - Oncodevelopmental Tumor Marker Deepti S. Wilkinson and Michelle Craig Barton 21 TGF-ß1: Roles in DNA Damage Responses Kumari L. Andarawewa, Julie Kirshner, Joni D. Mott, and Mary Helen Barcellos-Hoff 22 The Rationale For and Effects of Targeting TGF-beta for Glioma Therapy Anita B. Hjelmeland and Jeremy N. Rich 23 Tumor Suppressor Function of TGF-ß1 in T Cells Ramireddy Bommireddy and Thomas Doetschman 24 Therapeutic Effects of Adenovirus-mediated Gene Transfer of TGF-ß Signal Antagonists on Undesirable Epithelial-mesenchymal Transition and Neovascularization Shizuka Saika 25 Role of TGF-ß in Tumor Protection
Rezensionen
From the reviews:

"This volume ... provide readers with a detailed account of the role of TGF-beta in the development of various cancers in numerous organs. ... This will likely be of interest to those in the field as well as those who are new ... . will be of interest to researchers at all levels. The book will likely attract new researchers and students interested in becoming engaged in new frontiers of cancer therapy. ... This will be a great resource for researchers and clinicians ... ." (James P Luyendyk, Doody's Review Service, June, 2008)