-31%
98,95 €
Statt 143,99 €**
98,95 €
inkl. MwSt.
**Preis der gedruckten Ausgabe (Gebundenes Buch)
Sofort per Download lieferbar
Statt 143,99 €**
98,95 €
inkl. MwSt.
**Preis der gedruckten Ausgabe (Gebundenes Buch)
Sofort per Download lieferbar

Alle Infos zum eBook verschenken
Als Download kaufen
Statt 143,99 €**
-31%
98,95 €
inkl. MwSt.
**Preis der gedruckten Ausgabe (Gebundenes Buch)
Sofort per Download lieferbar
Abo Download
9,90 € / Monat*
*Abopreis beinhaltet vier eBooks, die aus der tolino select Titelauswahl im Abo geladen werden können.

inkl. MwSt.
Sofort per Download lieferbar

Einmalig pro Kunde einen Monat kostenlos testen (danach 9,90 € pro Monat), jeden Monat 4 aus 40 Titeln wählen, monatlich kündbar.

Mehr zum tolino select eBook-Abo
Jetzt verschenken
Statt 143,99 €**
-31%
98,95 €
inkl. MwSt.
**Preis der gedruckten Ausgabe (Gebundenes Buch)
Sofort per Download lieferbar

Alle Infos zum eBook verschenken
49 °P sammeln

  • Format: PDF


Diabetes mellitus has become epidemic on a global scale, and millions of new cases are diagnosed every year. The epidemic of diabetes mellitus is expected to result in one of the steepest rises in human morbidity and mortality ever observed outside of wartime. Insulin resistance is a hallmark of pre-diabetes and type 2 diabetes mellitus, and is characterized by impaired insulin-signaling transduction. Authoritative and comprehensive, Lipoproteins in Diabetes Mellitus details the many changes wrought by insulin resistance and diabetes mellitus on lipid and lipoprotein metabolism. The book…mehr

Produktbeschreibung
Diabetes mellitus has become epidemic on a global scale, and millions of new cases are diagnosed every year. The epidemic of diabetes mellitus is expected to result in one of the steepest rises in human morbidity and mortality ever observed outside of wartime. Insulin resistance is a hallmark of pre-diabetes and type 2 diabetes mellitus, and is characterized by impaired insulin-signaling transduction. Authoritative and comprehensive, Lipoproteins in Diabetes Mellitus details the many changes wrought by insulin resistance and diabetes mellitus on lipid and lipoprotein metabolism. The book begins by summarizing the various techniques to measure lipoproteins and their subclasses. The mechanisms by which insulin resistance and diabetes mellitus increase risk for atherosclerosis, diabetic retinopathy, and diabetic nephropathy are then explored in detail. Finally, the effects of lifestyle modification and the results of clinical trials using established and investigational drugs are discussed.

An invaluable contribution to the literature, Lipoproteins in Diabetes Mellitus is a comprehensive reference on the clinical and scientific aspects of lipoproteins in diabetes. It will have a long-lasting and significant effect on the medical management of people with diabetes.


Dieser Download kann aus rechtlichen Gründen nur mit Rechnungsadresse in A, B, BG, CY, CZ, D, DK, EW, E, FIN, F, GB, GR, HR, H, IRL, I, LT, L, LR, M, NL, PL, P, R, S, SLO, SK ausgeliefert werden.

  • Produktdetails
  • Verlag: Springer-Verlag GmbH
  • Erscheinungstermin: 08.01.2014
  • Englisch
  • ISBN-13: 9781461475545
  • Artikelnr.: 43799359
Autorenporträt
Alicia Jenkins, MBBS, MD, FRACP, FRCP
University of Oklahoma Health Sciences Center, Section of Endocrinology and Diabetes, Oklahoma City, OK, USA

Peter P. Toth, MD, PhD, FAAFP, FICA, FNLA, FCCP, FAHA, FACC
CGH Medical Center, Sterling, IL
University of Illinois College of Medicine, Clinical Family and Community Medicine, Peoria, IL
Michigan State University College of Osteopathic Medicine, Clinical Medicine, East Lansing, MI, USA

Timothy J. Lyons, MD, FRCP
University of Oklahoma Health Sciences Center, Section of Endocrinology and Diabetes, Harold Hamm Diabetes Center, Oklahoma City, OK, USA
Inhaltsangabe
Ch1: Laboratory Assessment of Lipoproteins in Diabetes David R. Sullivan Barry Lewis Ch2: Lipoprotein Subclasses and Cardiovascular Disease Risk in Insulin Resistance Diabetes Michael Cobble Patrick D. Mize Eliot A. Brinton Ch3: Insulin Resistance and Atherosclerosis Kamalpreet Singh Vasudevan A. Raghavan Ch4: Apoproteins and Cell Surface Receptors Regulating Lipoprotein Metabolism in the Setting of Type 2 Diabetes Thomas D. Dayspring Ch5: Lipoprotein Metabolism and Alterations induced by insulin resistance and diabetes Gerald H. Tomkin Daphne Owens Ch6: Production and Metabolism of Triglyceride-Rich Lipoproteins in both the Normal and Diabetic States Angela Pirillo Giuseppe D. Norata Alberico L. Catapano Ch7: Lipoprotein(a): Structure, Metabolism and Pathophysiology Alicia J. Jenkins Karam M. Kostner Gerhard M. Kostner Ch8: Lipoprotein Glycation in Diabetes Mellitus Alicia J. Jenkins Richard L. Klein Andrzej S. Januszewski Ch9: Lipoprotein (LDL and HDL) Oxidation in Diabetes Mellitus Marielle Kaplan Michael Aviram Tony Hayek Ch10: The Role of Modified Forms of LDL and Corresponding Autoantibodies in the Development of Complications in Diabetes Maria F. Lopes-Virella Gabriel Virella Ch11: Lipid - Extracellular Matrix Interactions as Therapeutic Targets in the Atherosclerosis of Diabetes Narin Osman Peter J. Little Ch12: Tools for Assessing Lipoprotein Metabolism in Diabetes Mellitus Richard L. Klein Ch13: Endothelial Dysfunction and Dyslipidaemia in Type 2 Diabetes: Pathogenesis, Significance and Therapy Sandra J. Hamilton Gerald F. Watts Ch14: Lipoproteins and Diabetic Nephropathy Ville-Petteri Mäkinen Nina Tolonen Per-Henrik Groop Ch15: Roles of Extravasated and Modified Plasma Lipoproteins in Diabetic Retinopathy Mingyuan Wu Timothy J. Lyons Ch16: Effects of Lifestyle (Diet, Plant Sterols, Excercise) and Glycemic Control on Lipoporteins in Diabetes Peter Clifton Ch17: About Randomised Clinical Trials Related to Lipoproteins in Diabetes Mellitus Anthony Keech Alicia J. Jenkins Val Gebski Ch18: Statin Therapy: Impact on Dyslipidemia and Cardiovascular Events in Diabetic Patients Seth S. Martin Parag H. Joshi Steven R. Jones Ch19: The PPAR System in Diabetes Jean Claude Ansquer Christelle Foucher Ch20: Fibrate Therapy: Impact on Dyslipidemia and Cardiovascular Events in Diabetic Patients Eliot A. Brinton Ch21: Niacin Therapy: Impact on Dyslipidemia and Cardiovascular Events in Diabetic Patients Henry A. Tran Arthur Z. Schwartzbard James A. Underberg Ch22: Cholesterol Absorption Inhibitors (Ezetimibe) and Bile Acid Binding Resins (Colesevelam HCl) as Therapy for Dyslipidemia in Patients with Diabetes Mellitus Harold Bays Ch23: Emerging Lipoprotein-Related Therapeutics for Patients with Diabetes Peter J. Little Alan Chait Andrzej S. Januszewski Alex Bobik David O'Neal Alicia J. Jenkins
Rezensionen
From the book reviews:
"This volume reviews in 23 chapters the lipid and lipoprotein changes induced by diabetes mellitus. It contains didactic color illustrations and many references. For clinical and research diabetologists, pharmacologists and biochemists." (Pediatric Endocrinology Reviews (PER), Vol. 12 (1), September, 2014)