L-Arginine in Clinical Nutrition

Herausgegeben:Patel, Vinood B.; Preedy, Victor R; Rajendram, Rajkumar

• Gebundenes Buch

Produktbeschreibung

Thistext presents the application of current nutritional knowledge by physiciansand dietitians and incorporates emerging fields of science and importantdiscoveries. It contains seven major sections.Section 1: Basic Processes at the Cellular Levels, Section 2: ArginineMetabolism and Functions, Section 3: Arginine Status in Cells Related to OrganDamage and Disease, Section 4: Arginine Status and Use in Healthy Individuals, Section5: Arginine and Diseases of the Gastrointestinal Tract, Section 6: Therapeuticuses of Arginine: Diabetes, Obesity and Cardiovascular Diseases and Section 7: Therapeutic Uses of Arginine: Cancer, WoundHealing and Infectious Disease.

Writtenby authors of international and national standing, leaders in the field andtrendsetters, Arginine in Clinical Nutrition is essential reading fornutritionists and dietitians, public health scientists, doctors,epidemiologists, health care professionals of various disciplines, policymakers and marketing and economic strategists.

Produktdetails

• Nutrition and Health
• Verlag: Humana / Springer International Publishing / Springer, Berlin
• Artikelnr. des Verlages: 978-3-319-26007-5
• 1st ed. 2017
• Seitenzahl: 676
• Erscheinungstermin: 2. September 2016
• Englisch
• Abmessung: 260mm x 183mm x 42mm
• Gewicht: 1377g
• ISBN-13: 9783319260075
• ISBN-10: 3319260073
• Artikelnr.: 43828313

Autorenporträt

Vinood B. Patel, BSc, PhD, FRSC University of Westminster Faculty of Science & Technology Department of Biomedical Sciences London, United Kingdom Victor R. Preedy, BSc, PhD, DSc Professor King's College London Dept Nutrition and Dietetics, Nutritional Sciences Division School of Biomedical & Health Sciences, Franklin-Wilkins Building London, United Kingdom Rajkumar Rajendram, AKC, BSc (Hons), MBBS (Dist), MRCP (UK), FRCA, EDIC, FFICM Nutritional Sciences Research Division Faculty of Life Science and Medicine King's College London Franklin-Wilkins Building London, United Kingdom

Inhaltsangabe

Section 1: Basic Processes at theCellular Levels.- Arginineuptake by cells.- L-arginine and theexpression of HSP70 and p-53 proteins.- AMP-activatedprotein kinase and L-arginine.- Amidine-basedcompounds affecting arginine metabolism.-Oxy- and sulfoanalogues of L-arginine.-Regulation of expression and activity of L-arginine transporters bynutrients and hormones: A focus in transcriptional mechanisms regulated byglucose and insulin.- Arginine, pancreatic beta cell function anddiabetes: mechanisms of stimulated insulin release and pathways of metabolism.- Erythrocytesby-products of arginine catabolism.- Section 2: Arginine Metabolismand Functions.- Argininesynthesis from enteral proline.- Arginineand macrophages: role in classical and alternative activation.- Arginineand TNF alpha production in macrophages: a focus on metabolism, ageing,metabolic syndrome and type 2 diabetes.- Argininemetabolism impairment during sepsis and diseases: causes and consequences.-Use of argininewith Growth Hormone Releasing Hormone (GHRH) and the endocrine response.- Serumarginase in healthy subjects and nitric oxide.- Section 3: Arginine Status in Cells Related to Organ Damage andDisease.- Protein Arginine Methylation of RNA-binding Proteins and TheirImpact on Human Diseases.- DNA-arginineadducts and implications in disease.- Homoarginineand L-arginine: Glycine amidinotransferase in stroke.- The L-arginine/asymmetric dimethylarginine (ADMA) ratio inhealth and disease: an overview.- Arginineand its transporters in colorectal cancer.-Arginine Uptake and Its Role in the Survival of Breast Cancer Cells.- Section 4: Arginine Status and Use inHealthy Individuals.- Arginine production during pregnancy.- L-arginine in the uterus andplacenta and during gestation in mammals.-Oral L-arginine supplementation in young males: endocrinology, metabolic,and physiological responses at rest and during exercise.- Metabolicprecursors of L-Arginine supplementation in sport: a focus on L-Citrulline andL-Ornithine.- Section 5: Arginine andDiseases of the Gastrointestinal Tract.- Arginine and its use in ameliorating Cryptosporidium parvum infection inundernourished children.- Arginineand Inflammatory Bowel Disease (IBD) .- Dietary L-arginine and intestinalrecovery.- Enteral andparenteral arginine supplementation in intestinal ischemia and reperfusioninjury.- Mucosal Protection byArginine in the Upper Gastrointestinal Tract.- Enteral L-arginine and necrotizing enterocolitis.- Section 6: Therapeutic uses of Arginine:Diabetes, Obesity and Cardiovascular Diseases.- L-arginine usage in Type Idiabetes: From the autoimmune event to human dietary supplementation.- Oral l-arginine supplementation andglucose metabolism and vascular function.-Arginine enriched apples and diabetic control.- Beneficial impact of cod protein, arginine and otheramino acids on insulin sensitivity.- Obese subjects and supplementalL-arginine.- Mitochondrial cardiomyopathyand usage of L-arginine.- ArginineMeasurement and Concentrations in Hypertension and other Cardiovascular Disease.- L-Arginineand cardiovascular disease.- Arginine therapy in sickle celldisease.- Section 7: Therapeutic Uses of Arginine: Cancer, WoundHealing and Infectious Disease.- Role of arginine in surgicalpatients with head and neck cancer.- Arginine-IncorporatedAlbumin Mesospheres: A Drug Delivery System for Cancer Therapy.- Use of L-arginine and glycinesupplementation to reduce radiotherapy damage.- Arginine in Cancer Therapy.- Mechanisms of Arginine-AuxotrophicResponse and Their Cancer Therapeutic Implications.- The role of arginine in wound healing.- L-arginine and bacterial translocation: implications for health.- L-arginine in Pulmonary Tuberculosis.- Argininein Health and Disease: Recommended Resources and Further Reading.

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Section 1: Basic Processes at the Cellular Levels.- Arginine uptake by cells.- L-arginine and the expression of HSP70 and p-53 proteins.- AMP-activated protein kinase and L-arginine.- Amidine-based compounds affecting arginine metabolism.- Oxy- and sulfoanalogues of L-arginine.- Regulation of expression and activity of L-arginine transporters by nutrients and hormones: A focus in transcriptional mechanisms regulated by glucose and insulin.- Arginine, pancreatic beta cell function and diabetes: mechanisms of stimulated insulin release and pathways of metabolism.- Erythrocytes by-products of arginine catabolism.- Section 2: Arginine Metabolism and Functions.- Arginine synthesis from enteral proline.- Arginine and macrophages: role in classical and alternative activation.- Arginine and TNF alpha production in macrophages: a focus on metabolism, ageing, metabolic syndrome and type 2 diabetes.- Arginine metabolism impairment during sepsis and diseases: causes and consequences.- Use of arginine with Growth Hormone Releasing Hormone (GHRH) and the endocrine response.- Serum arginase in healthy subjects and nitric oxide.- Section 3: Arginine Status in Cells Related to Organ Damage and Disease.- Protein Arginine Methylation of RNA-binding Proteins and Their Impact on Human Diseases.- DNA-arginine adducts and implications in disease.- Homoarginine and L-arginine: Glycine amidinotransferase in stroke.- The L-arginine/asymmetric dimethylarginine (ADMA) ratio in health and disease: an overview.- Arginine and its transporters in colorectal cancer.- Arginine Uptake and Its Role in the Survival of Breast Cancer Cells.- Section 4: Arginine Status and Use in Healthy Individuals.- Arginine production during pregnancy.- L-arginine in the uterus and placenta and during gestation in mammals.- Oral L-arginine supplementation in young males: endocrinology, metabolic, and physiological responses at rest and during exercise.- Metabolic precursors of L-Arginine supplementation in sport: a focus on L-Citrulline and L-Ornithine.- Section 5: Arginine and Diseases of the Gastrointestinal Tract.- Arginine and its use in ameliorating Cryptosporidium parvum infection in undernourished children.- Arginine and Inflammatory Bowel Disease (IBD) .- Dietary L-arginine and intestinal recovery.- Enteral and parenteral arginine supplementation in intestinal ischemia and reperfusion injury.- Mucosal Protection by Arginine in the Upper Gastrointestinal Tract.- Enteral L-arginine and necrotizing enterocolitis.- Section 6: Therapeutic uses of Arginine: Diabetes, Obesity and Cardiovascular Diseases.- L-arginine usage in Type I diabetes: From the autoimmune event to human dietary supplementation.- Oral l-arginine supplementation and glucose metabolism and vascular function.- Arginine enriched apples and diabetic control.- Beneficial impact of cod protein, arginine and other amino acids on insulin sensitivity.- Obese subjects and supplemental L-arginine.- Mitochondrial cardiomyopathy and usage of L-arginine.- Arginine Measurement and Concentrations in Hypertension and other Cardiovascular Disease.- L-Arginine and cardiovascular disease.- Arginine therapy in sickle cell disease.- Section 7: Therapeutic Uses of Arginine: Cancer, Wound Healing and Infectious Disease.- Role of arginine in surgical patients with head and neck cancer.- Arginine-Incorporated Albumin Mesospheres: A Drug Delivery System for Cancer Therapy.- Use of L-arginine and glycine supplementation to reduce radiotherapy damage.- Arginine in Cancer Therapy.- Mechanisms of Arginine-Auxotrophic Response and Their Cancer Therapeutic Implications.- The role of arginine in wound healing.- L-arginine and bacterial translocation: implications for health.- L-arginine in Pulmonary Tuberculosis.- Arginine in Health and Disease: Recommended Resources and Further Reading.