Moyamoya Disease Explored Through RNF213
Genetics, Molecular Pathology, and Clinical Sciences
Herausgegeben:Koizumi, Akio; Nagata, Kazuhiro; Houkin, Kiyohiro; Tominaga, Teiji; Miyamoto, Susumu; Kure, Shigeo; Tournier-Lasserve, Elizabeth
Moyamoya Disease Explored Through RNF213
Genetics, Molecular Pathology, and Clinical Sciences
Herausgegeben:Koizumi, Akio; Nagata, Kazuhiro; Houkin, Kiyohiro; Tominaga, Teiji; Miyamoto, Susumu; Kure, Shigeo; Tournier-Lasserve, Elizabeth
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This book presents the latest findings on biological, epidemiological, and clinical investigations of RNF213, which is thought to be involved in many biological processes and plays a key role in cerebro- and cardiovascular disease . By discussing the epidemiology and genetic epidemiology of the disease with a particular focus on the molecular function of RNF213, research using animal models, diagnosis, therapy and clinical management around the world, this work makes a valuable contribution to the study of the disease.Moyamoya Disease Explored Through RNF213 is an indispensable resource for…mehr
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- Produktdetails
- Current Topics in Environmental Health and Preventive Medicine
- Verlag: Springer / Springer Nature Singapore / Springer, Berlin
- Artikelnr. des Verlages: 978-981-10-2710-9
- 1st ed. 2017
- Seitenzahl: 196
- Erscheinungstermin: 2. März 2017
- Englisch
- Abmessung: 241mm x 160mm x 16mm
- Gewicht: 444g
- ISBN-13: 9789811027109
- ISBN-10: 9811027102
- Artikelnr.: 45639112
- Current Topics in Environmental Health and Preventive Medicine
- Verlag: Springer / Springer Nature Singapore / Springer, Berlin
- Artikelnr. des Verlages: 978-981-10-2710-9
- 1st ed. 2017
- Seitenzahl: 196
- Erscheinungstermin: 2. März 2017
- Englisch
- Abmessung: 241mm x 160mm x 16mm
- Gewicht: 444g
- ISBN-13: 9789811027109
- ISBN-10: 9811027102
- Artikelnr.: 45639112
1. A prologue to moyamoya disease and RNF213.-
2. Concept of moyamoya Disease.-
Part II: Genetic Epidemiology.-
3. Molecular Epidemiology in East Asian Countries and in the World.-
Part III: Biochemistry, Function and Molecular Pathology.-
4. Molecular Biology of Mysterin/RNF213.-
5. Physiological Role of Mysterin/RNF213 in Zebrafish.-
6. Pathological Investigation on RNF213: Animal Models Knockout and Transgenic Mice in Diabetes and Signal Transduction.-
7. Pathological Investigation on RNF213: Animal Models of Rnf213-knockout and Knock-in Mice.-
8. RNF213 and Circulating Factors in Patients with Moyamoya Disease .-
9. Genetics of Moyamoya beyond RNF213. Monogenic Moyamoya Syndromes.-
Part IV: Clinical Management
10. Natural History and Long-term Clinical Outcome after Conservative and Surgical Management.-
11. Significance of RNF213 in Clinical Management in Japan.-
12. Significance of RNF213 in Clinical Management in China.-
13. The Different Forms of Moyamoya Disease and Their Clinical Management.-
14. Vascular Diseases Attributable to RNF213 Other than Moyamoya Disease.-
Part V: Epilogue.-
Future Clinical Perspectives on RNF213 in Moyamoya Disease.
1. A prologue to moyamoya disease and RNF213.-
2. Concept of moyamoya Disease.-
Part II: Genetic Epidemiology.-
3. Molecular Epidemiology in East Asian Countries and in the World.-
Part III: Biochemistry, Function and Molecular Pathology.-
4. Molecular Biology of Mysterin/RNF213.-
5. Physiological Role of Mysterin/RNF213 in Zebrafish.-
6. Pathological Investigation on RNF213: Animal Models Knockout and Transgenic Mice in Diabetes and Signal Transduction.-
7. Pathological Investigation on RNF213: Animal Models of Rnf213-knockout and Knock-in Mice.-
8. RNF213 and Circulating Factors in Patients with Moyamoya Disease .-
9. Genetics of Moyamoya beyond RNF213. Monogenic Moyamoya Syndromes.-
Part IV: Clinical Management
10. Natural History and Long-term Clinical Outcome after Conservative and Surgical Management.-
11. Significance of RNF213 in Clinical Management in Japan.-
12. Significance of RNF213 in Clinical Management in China.-
13. The Different Forms of Moyamoya Disease and Their Clinical Management.-
14. Vascular Diseases Attributable to RNF213 Other than Moyamoya Disease.-
Part V: Epilogue.-
Future Clinical Perspectives on RNF213 in Moyamoya Disease.
1. A prologue to moyamoya disease and RNF213.-
2. Concept of moyamoya Disease.-
Part II: Genetic Epidemiology.-
3. Molecular Epidemiology in East Asian Countries and in the World.-
Part III: Biochemistry, Function and Molecular Pathology.-
4. Molecular Biology of Mysterin/RNF213.-
5. Physiological Role of Mysterin/RNF213 in Zebrafish.-
6. Pathological Investigation on RNF213: Animal Models Knockout and Transgenic Mice in Diabetes and Signal Transduction.-
7. Pathological Investigation on RNF213: Animal Models of Rnf213-knockout and Knock-in Mice.-
8. RNF213 and Circulating Factors in Patients with Moyamoya Disease .-
9. Genetics of Moyamoya beyond RNF213. Monogenic Moyamoya Syndromes.-
Part IV: Clinical Management
10. Natural History and Long-term Clinical Outcome after Conservative and Surgical Management.-
11. Significance of RNF213 in Clinical Management in Japan.-
12. Significance of RNF213 in Clinical Management in China.-
13. The Different Forms of Moyamoya Disease and Their Clinical Management.-
14. Vascular Diseases Attributable to RNF213 Other than Moyamoya Disease.-
Part V: Epilogue.-
Future Clinical Perspectives on RNF213 in Moyamoya Disease.
1. A prologue to moyamoya disease and RNF213.-
2. Concept of moyamoya Disease.-
Part II: Genetic Epidemiology.-
3. Molecular Epidemiology in East Asian Countries and in the World.-
Part III: Biochemistry, Function and Molecular Pathology.-
4. Molecular Biology of Mysterin/RNF213.-
5. Physiological Role of Mysterin/RNF213 in Zebrafish.-
6. Pathological Investigation on RNF213: Animal Models Knockout and Transgenic Mice in Diabetes and Signal Transduction.-
7. Pathological Investigation on RNF213: Animal Models of Rnf213-knockout and Knock-in Mice.-
8. RNF213 and Circulating Factors in Patients with Moyamoya Disease .-
9. Genetics of Moyamoya beyond RNF213. Monogenic Moyamoya Syndromes.-
Part IV: Clinical Management
10. Natural History and Long-term Clinical Outcome after Conservative and Surgical Management.-
11. Significance of RNF213 in Clinical Management in Japan.-
12. Significance of RNF213 in Clinical Management in China.-
13. The Different Forms of Moyamoya Disease and Their Clinical Management.-
14. Vascular Diseases Attributable to RNF213 Other than Moyamoya Disease.-
Part V: Epilogue.-
Future Clinical Perspectives on RNF213 in Moyamoya Disease.