Martha Eibl / W.R. Mayr / G.J. Thorbecke (eds.)

Epitope Recognition Since Landsteiner¿s Discovery

100 Years Since the Discovery of Human Blood Groups
Ed. by Martha Eibl, W. R. Mayr and G. J. Thorbecke

• Broschiertes Buch

Produktbeschreibung

Karl Landsteiner is best known for his discovery of the human blood goups. The revolutionary discoveries of this brilliant scientist in other fields have not received the recognition they deserve. His demonstration that poliomyelitis is transmissable showed the way of modern virology. His studies opening the field for epitope recognition, which he himself considered his main achievement, laid the foundation for research ongoing in our days. This book with its outstanding contributors is but a small tribute to this visionary scientist.

Produktdetails

• Verlag: Springer / Springer Berlin Heidelberg / Springer, Berlin
• Artikelnr. des Verlages: 978-3-540-42651-6
• 2002
• Seitenzahl: 140
• Erscheinungstermin: 11. April 2002
• Englisch
• Abmessung: 235mm x 155mm x 8mm
• Gewicht: 286g
• ISBN-13: 9783540426516
• ISBN-10: 3540426515
• Artikelnr.: 10490561

Autorenporträt

Martha Eibl, Biomedizinische Forschungsgesellschaft mbH, Vienna, Austria / W.R. Mayr, Allgemeines Krankenhaus der Stadt Wien, Vienna, Austria / G.J. Thorbecke, New York University School of Medicine, New York, NY, USA

Inhaltsangabe

Introduction.-Landsteiner in Vienna.-Antigen Recognition: 100 years after Landsteiner.-Induction and suppression of an autoimmune disease by oligomerized T cell epitopes: Enhanced in vivo potency of encephalitogenic peptides.-Determination of the expresssed T cell repertoire: The outcome of competition at the levels of antigen presentation and T cell receptor recognition.-Using monoclonal antibodies and site directed mutagenesis to map the epitopes of the blood group Rh D antigen.-Infections and the immune response to cardiac antigens.-Subject index