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Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics Tarik Regad, The John van Geest Cancer Research Centre, Nottingham Trent University, UK, Thomas J. Sayers, Centre for Cancer Research, National Cancer Institute, Frederick, USA and Robert Rees The John van Geest Cancer Research Centre, Nottingham Trent University, UK The field of cancer stem cells is expanding rapidly, with many groups focusing on isolating and identifying cancer stem cell populations. Although some progress has been made developing efficient cancer therapies, targeting cancer stem cells remains…mehr

Produktbeschreibung
Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics Tarik Regad, The John van Geest Cancer Research Centre, Nottingham Trent University, UK, Thomas J. Sayers, Centre for Cancer Research, National Cancer Institute, Frederick, USA and Robert Rees The John van Geest Cancer Research Centre, Nottingham Trent University, UK The field of cancer stem cells is expanding rapidly, with many groups focusing on isolating and identifying cancer stem cell populations. Although some progress has been made developing efficient cancer therapies, targeting cancer stem cells remains one of the important challenges facing the growing stem cell research community. Principles of Stem Cell Biology and Cancer brings together original contributions from international experts in the field to present the very latest information linking stem cell biology and cancer. Divided into two parts, the book begins with a detailed introduction to stem cell biology with a focus on the characterization of these cells, progress that has been made in their identification, as well as future therapeutic applications of stem cells. The second part focuses on cancer stem cells and their role in cancer development, progression and chemo-resistance. This section of the book includes an overview of recent progress concerning therapies targeting cancer stem cells. Features: An authoritative introduction to the link between stem cell biology and cancer. Includes contributions from leading international experts in the field. Well-illustrated with full colour figures throughout. This book will prove an invaluable resource for basic and applied researchers and clinicians working on the development of new cancer treatments and therapies, providing a timely publication of high quality reviews outlining the current progress and exciting future possibilities for stem cell research.

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  • Produktdetails
  • Verlag: John Wiley & Sons
  • Seitenzahl: 376
  • Erscheinungstermin: 01.04.2015
  • Englisch
  • ISBN-13: 9781118670606
  • Artikelnr.: 42739268
Autorenporträt
Tarik Regad, The John van Geest Cancer Research Centre, Nottingham Trent University, Nottingham, UK Thomas J. Sayers, Leidos Biomedical Research Inc., and the Cancer and Infl ammation Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA Robert C. Rees, The John van Geest Cancer Research Centre, Nottingham Trent University, Nottingham, UK
Inhaltsangabe
Preface
1. Isolation and characterisation of embryonic stem cells and future applications in tissue engineering therapies
2. Epigenetics, stem cell pluripotency and differentiation
3. Stem cell niche and microenvironment
4. Hematopoietic stem cells in therapy
5. Isolation and Identification of neural stem/progenitor cells
6. The Role of Epithelial-Mesenchymal Transition in Cancer Metastasis
7. Regulation of Breast Cancer Stem Cells by Mesenchymal Stem Cells in the Metastatic Niche
8. Isolation and identification of neural cancer stem/progenitor cells
9. Colon stem cells in colorectal cancer
10. Prostate cancer and prostate cancer stem cells
11. Stem cells and pancreatic cancer
12. NANOG in cancer development
13. Liver cancer stem cells and hepatocarcinogenesis
14. The Basic Science of Liver Cancer Stem Cells and Hepatocarcinogenesis
15. Cancer stem cells biomarkers
16. Interatomic analysis of the stem cell marker NANOG in a prostate cancer setting
Index