- Gebundenes Buch
- Merkliste
- Auf die Merkliste
- Bewerten Bewerten
- Teilen
- Produkt teilen
- Produkterinnerung
- Produkterinnerung
Current applications and recent advances in genomics and proteomics
Genomics and Proteomics Engineering in Medicine and Biology presents a well-rounded, interdisciplinary discussion of a topic that is at the cutting edge of both molecular biology and bioengineering. Compiling contributions by established experts, this book highlights up-to-date applications of biomedical informatics, as well as advancements in genomics-proteomics areas. Structures and algorithms are used to analyze genomic data and develop computational solutions for pathological understanding.
Topics discussed include:…mehr
Andere Kunden interessierten sich auch für
- Chemical and Functional Genomic Approaches to Stem Cell Biology and Regenerative Medicine132,99 €
- Data Analysis and Visualization in Genomics and Proteomics201,99 €
- Gordana Vunjak-Novakovic / R. Ian Freshney (Hgg.)Culture of Cells for Tissue Engineering177,99 €
- Charles R. CantorGenomics267,99 €
- Stuart M. BrownEssentials of Medical Genomics143,99 €
- Proteomics140,99 €
- Laser Imaging and Manipulation in Cell Biology147,99 €
-
-
-
Current applications and recent advances in genomics and proteomics
Genomics and Proteomics Engineering in Medicine and Biology presents a well-rounded, interdisciplinary discussion of a topic that is at the cutting edge of both molecular biology and bioengineering. Compiling contributions by established experts, this book highlights up-to-date applications of biomedical informatics, as well as advancements in genomics-proteomics areas. Structures and algorithms are used to analyze genomic data and develop computational solutions for pathological understanding.
Topics discussed include:
_ Qualitative knowledge models
_ Interpreting micro-array data
_ Gene regulation bioinformatics
_ Methods to analyze micro-array
_ Cancer behavior and radiation therapy
_ Error-control codes and the genome
_ Complex life science multi-database queries
_ Computational protein analysis
_ Tumor and tumor suppressor proteins interactions
Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Genomics and Proteomics Engineering in Medicine and Biology presents a well-rounded, interdisciplinary discussion of a topic that is at the cutting edge of both molecular biology and bioengineering. Compiling contributions by established experts, this book highlights up-to-date applications of biomedical informatics, as well as advancements in genomics-proteomics areas. Structures and algorithms are used to analyze genomic data and develop computational solutions for pathological understanding.
Topics discussed include:
_ Qualitative knowledge models
_ Interpreting micro-array data
_ Gene regulation bioinformatics
_ Methods to analyze micro-array
_ Cancer behavior and radiation therapy
_ Error-control codes and the genome
_ Complex life science multi-database queries
_ Computational protein analysis
_ Tumor and tumor suppressor proteins interactions
Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Produktdetails
- Produktdetails
- IEEE Press Series on Biomedical Engineering
- Verlag: Wiley & Sons
- 1. Auflage
- Seitenzahl: 450
- Erscheinungstermin: 1. Dezember 2006
- Englisch
- Abmessung: 235mm x 161mm x 20mm
- Gewicht: 580g
- ISBN-13: 9780471631811
- ISBN-10: 0471631817
- Artikelnr.: 20930896
- IEEE Press Series on Biomedical Engineering
- Verlag: Wiley & Sons
- 1. Auflage
- Seitenzahl: 450
- Erscheinungstermin: 1. Dezember 2006
- Englisch
- Abmessung: 235mm x 161mm x 20mm
- Gewicht: 580g
- ISBN-13: 9780471631811
- ISBN-10: 0471631817
- Artikelnr.: 20930896
METIN AKAY, PHD, is the Interim Chair and Professor of Bioengineering for the Harrington Department of Bioengineering at the Arizona State University. Dr. Akay is the founding Series Editor of the IEEE Press Series on Biomedical Engineering. In 1997, he received the prestigious Early Career Achievement Award from the IEEE Engineering in Medicine and Biology Society (EMBS). He was the program chair of both the annual IEEE EMBS Conference and Summer School for 2001. Dr. Akay has published several papers in the field and authored, coauthored, or edited fourteen books. He is also the editor in chief of the Wiley Encyclopedia of Biomedical Engineering.
Preface. Contributors. 1. Qualitative Knowledge Models in Functional
Genomics and Proteomics (Mor Peleg, Irene S. Gabashvili, and Russ B.
Altman). 1.1. Introduction. 1.2. Methods and Tools. 1.3. Modeling Approach
and Results. 1.4. Discussion. 1.5. Conclusion. References. 2. Interpreting
Microarray Data and Related Applications Using Nonlinear System
Identification (Michael Korenberg). 2.1. Introduction. 2.2. Background.
2.3. Parallel Cascade Identification. 2.4. Constructing Class Predictors.
2.5. Prediction Based on Gene Expression Profiling. 2.6. Comparing
Different Predictors Over the Same Data Set. 2.7. Concluding Remarks.
References. 3. Gene Regulation Bioinformatics of Microarray Data (Gert
Thijs, Frank De Smet, Yves Moreau, Kathleen Marchal, and Bart De Moor).
3.1. Introduction. 3.2. Introduction to Transcriptional Regulation. 3.3.
Measuring Gene Expression Profiles. 3.4. Preprocessing of Data. 3.5.
Clustering of Gene Expression Profiles. 3.6. Cluster Validation. 3.7.
Searching for Common Binding Sites of Coregulated Genes. 3.8. Inclusive:
Online Integrated Analysis of Microarray Data. 3.9. Further Integrative
Steps. 3.10. Conclusion. References. 4. Robust Methods for Microarray
Analysis (George S. Davidson, Shawn Martin, Kevin W. Boyack, Brian N.
Wylie, Juanita Martinez, Anthony Aragon, Margaret Werner-Washburne, Mönica
Mosquera-Caro, and Cheryl Willman). 4.1. Introduction. 4.2. Microarray
Experiments and Analysis Methods. 4.3. Unsupervised Methods. 4.4.
Supervised Methods. 4.5. Conclusion. References. 5. In Silico Radiation
Oncology: A Platform for Understanding Cancer Behavior and Optimizing
Radiation Therapy Treatment (G. Stamatakos, D. Dionysiou, and N. Uzunoglu).
5.1. Philosophiae Tumoralis Principia Algorithmica: Algorithmic Principles
of Simulating Cancer on Computer. 5.2. Brief Literature Review. 5.3.
Paradigm of Four-Dimensional Simulation of Tumor Growth and Response to
Radiation Therapy In Vivo. 5.4. Discussion. 5.5. Future Trends. References.
6. Genomewide Motif Identification Using a Dictionary Model (Chiara Sabatti
and Kenneth Lange). 6.1. Introduction. 6.2. Unified Model. 6.3. Algorithms
for Likelihood Evaluation. 6.4. Parameter Estimation via
Minorization-Maximization Algorithm. 6.5. Examples. 6.6. Discussion and
Conclusion. References. 7. Error Control Codes and the Genome (Elebeoba E.
May). 7.1. Error Control and Communication: A Review. 7.3. Reverse
Engineering the Genetic Error Control System. 7.4. Applications of
Biological Coding Theory. References. 8. Complex Life Science Multidatabase
Queries (Zina Ben Miled, Nianhua Li, Yue He, Malika Mahoui, and Omran
Bukhres). 8.1. Introduction. 8.2. Architecture. 8.3. Query Execution Plans.
8.4. Related Work. 8.5. Future Trends. References. 9. Computational
Analysis of Proteins (Dimitrios I. Fotiadis, Yorgos Goletsis, Christos
Lampros, and Costas Papaloukas). 9.1. Introduction: Definitions. 9.2.
Databases. 9.3. Sequence Motifs and Domains. 9.4. Sequence Alignment. 9.5.
Modeling. 9.6. Classification and Prediction. 9.7. Natural Language
Processing. 9.8. Future Trends. References. 10. Computational Analysis of
Interactions Between Tumor and Tumor Suppressor Proteins (E. Pirogova, M.
Akay, and I. Cosic). 10.1. Introduction. 10.2. Methodology: Resonant
Recognition Model. 10.3. Results and Discussions. 10.4. Conclusion.
References. Index. About the Editor.
Genomics and Proteomics (Mor Peleg, Irene S. Gabashvili, and Russ B.
Altman). 1.1. Introduction. 1.2. Methods and Tools. 1.3. Modeling Approach
and Results. 1.4. Discussion. 1.5. Conclusion. References. 2. Interpreting
Microarray Data and Related Applications Using Nonlinear System
Identification (Michael Korenberg). 2.1. Introduction. 2.2. Background.
2.3. Parallel Cascade Identification. 2.4. Constructing Class Predictors.
2.5. Prediction Based on Gene Expression Profiling. 2.6. Comparing
Different Predictors Over the Same Data Set. 2.7. Concluding Remarks.
References. 3. Gene Regulation Bioinformatics of Microarray Data (Gert
Thijs, Frank De Smet, Yves Moreau, Kathleen Marchal, and Bart De Moor).
3.1. Introduction. 3.2. Introduction to Transcriptional Regulation. 3.3.
Measuring Gene Expression Profiles. 3.4. Preprocessing of Data. 3.5.
Clustering of Gene Expression Profiles. 3.6. Cluster Validation. 3.7.
Searching for Common Binding Sites of Coregulated Genes. 3.8. Inclusive:
Online Integrated Analysis of Microarray Data. 3.9. Further Integrative
Steps. 3.10. Conclusion. References. 4. Robust Methods for Microarray
Analysis (George S. Davidson, Shawn Martin, Kevin W. Boyack, Brian N.
Wylie, Juanita Martinez, Anthony Aragon, Margaret Werner-Washburne, Mönica
Mosquera-Caro, and Cheryl Willman). 4.1. Introduction. 4.2. Microarray
Experiments and Analysis Methods. 4.3. Unsupervised Methods. 4.4.
Supervised Methods. 4.5. Conclusion. References. 5. In Silico Radiation
Oncology: A Platform for Understanding Cancer Behavior and Optimizing
Radiation Therapy Treatment (G. Stamatakos, D. Dionysiou, and N. Uzunoglu).
5.1. Philosophiae Tumoralis Principia Algorithmica: Algorithmic Principles
of Simulating Cancer on Computer. 5.2. Brief Literature Review. 5.3.
Paradigm of Four-Dimensional Simulation of Tumor Growth and Response to
Radiation Therapy In Vivo. 5.4. Discussion. 5.5. Future Trends. References.
6. Genomewide Motif Identification Using a Dictionary Model (Chiara Sabatti
and Kenneth Lange). 6.1. Introduction. 6.2. Unified Model. 6.3. Algorithms
for Likelihood Evaluation. 6.4. Parameter Estimation via
Minorization-Maximization Algorithm. 6.5. Examples. 6.6. Discussion and
Conclusion. References. 7. Error Control Codes and the Genome (Elebeoba E.
May). 7.1. Error Control and Communication: A Review. 7.3. Reverse
Engineering the Genetic Error Control System. 7.4. Applications of
Biological Coding Theory. References. 8. Complex Life Science Multidatabase
Queries (Zina Ben Miled, Nianhua Li, Yue He, Malika Mahoui, and Omran
Bukhres). 8.1. Introduction. 8.2. Architecture. 8.3. Query Execution Plans.
8.4. Related Work. 8.5. Future Trends. References. 9. Computational
Analysis of Proteins (Dimitrios I. Fotiadis, Yorgos Goletsis, Christos
Lampros, and Costas Papaloukas). 9.1. Introduction: Definitions. 9.2.
Databases. 9.3. Sequence Motifs and Domains. 9.4. Sequence Alignment. 9.5.
Modeling. 9.6. Classification and Prediction. 9.7. Natural Language
Processing. 9.8. Future Trends. References. 10. Computational Analysis of
Interactions Between Tumor and Tumor Suppressor Proteins (E. Pirogova, M.
Akay, and I. Cosic). 10.1. Introduction. 10.2. Methodology: Resonant
Recognition Model. 10.3. Results and Discussions. 10.4. Conclusion.
References. Index. About the Editor.
Preface. Contributors. 1. Qualitative Knowledge Models in Functional
Genomics and Proteomics (Mor Peleg, Irene S. Gabashvili, and Russ B.
Altman). 1.1. Introduction. 1.2. Methods and Tools. 1.3. Modeling Approach
and Results. 1.4. Discussion. 1.5. Conclusion. References. 2. Interpreting
Microarray Data and Related Applications Using Nonlinear System
Identification (Michael Korenberg). 2.1. Introduction. 2.2. Background.
2.3. Parallel Cascade Identification. 2.4. Constructing Class Predictors.
2.5. Prediction Based on Gene Expression Profiling. 2.6. Comparing
Different Predictors Over the Same Data Set. 2.7. Concluding Remarks.
References. 3. Gene Regulation Bioinformatics of Microarray Data (Gert
Thijs, Frank De Smet, Yves Moreau, Kathleen Marchal, and Bart De Moor).
3.1. Introduction. 3.2. Introduction to Transcriptional Regulation. 3.3.
Measuring Gene Expression Profiles. 3.4. Preprocessing of Data. 3.5.
Clustering of Gene Expression Profiles. 3.6. Cluster Validation. 3.7.
Searching for Common Binding Sites of Coregulated Genes. 3.8. Inclusive:
Online Integrated Analysis of Microarray Data. 3.9. Further Integrative
Steps. 3.10. Conclusion. References. 4. Robust Methods for Microarray
Analysis (George S. Davidson, Shawn Martin, Kevin W. Boyack, Brian N.
Wylie, Juanita Martinez, Anthony Aragon, Margaret Werner-Washburne, Mönica
Mosquera-Caro, and Cheryl Willman). 4.1. Introduction. 4.2. Microarray
Experiments and Analysis Methods. 4.3. Unsupervised Methods. 4.4.
Supervised Methods. 4.5. Conclusion. References. 5. In Silico Radiation
Oncology: A Platform for Understanding Cancer Behavior and Optimizing
Radiation Therapy Treatment (G. Stamatakos, D. Dionysiou, and N. Uzunoglu).
5.1. Philosophiae Tumoralis Principia Algorithmica: Algorithmic Principles
of Simulating Cancer on Computer. 5.2. Brief Literature Review. 5.3.
Paradigm of Four-Dimensional Simulation of Tumor Growth and Response to
Radiation Therapy In Vivo. 5.4. Discussion. 5.5. Future Trends. References.
6. Genomewide Motif Identification Using a Dictionary Model (Chiara Sabatti
and Kenneth Lange). 6.1. Introduction. 6.2. Unified Model. 6.3. Algorithms
for Likelihood Evaluation. 6.4. Parameter Estimation via
Minorization-Maximization Algorithm. 6.5. Examples. 6.6. Discussion and
Conclusion. References. 7. Error Control Codes and the Genome (Elebeoba E.
May). 7.1. Error Control and Communication: A Review. 7.3. Reverse
Engineering the Genetic Error Control System. 7.4. Applications of
Biological Coding Theory. References. 8. Complex Life Science Multidatabase
Queries (Zina Ben Miled, Nianhua Li, Yue He, Malika Mahoui, and Omran
Bukhres). 8.1. Introduction. 8.2. Architecture. 8.3. Query Execution Plans.
8.4. Related Work. 8.5. Future Trends. References. 9. Computational
Analysis of Proteins (Dimitrios I. Fotiadis, Yorgos Goletsis, Christos
Lampros, and Costas Papaloukas). 9.1. Introduction: Definitions. 9.2.
Databases. 9.3. Sequence Motifs and Domains. 9.4. Sequence Alignment. 9.5.
Modeling. 9.6. Classification and Prediction. 9.7. Natural Language
Processing. 9.8. Future Trends. References. 10. Computational Analysis of
Interactions Between Tumor and Tumor Suppressor Proteins (E. Pirogova, M.
Akay, and I. Cosic). 10.1. Introduction. 10.2. Methodology: Resonant
Recognition Model. 10.3. Results and Discussions. 10.4. Conclusion.
References. Index. About the Editor.
Genomics and Proteomics (Mor Peleg, Irene S. Gabashvili, and Russ B.
Altman). 1.1. Introduction. 1.2. Methods and Tools. 1.3. Modeling Approach
and Results. 1.4. Discussion. 1.5. Conclusion. References. 2. Interpreting
Microarray Data and Related Applications Using Nonlinear System
Identification (Michael Korenberg). 2.1. Introduction. 2.2. Background.
2.3. Parallel Cascade Identification. 2.4. Constructing Class Predictors.
2.5. Prediction Based on Gene Expression Profiling. 2.6. Comparing
Different Predictors Over the Same Data Set. 2.7. Concluding Remarks.
References. 3. Gene Regulation Bioinformatics of Microarray Data (Gert
Thijs, Frank De Smet, Yves Moreau, Kathleen Marchal, and Bart De Moor).
3.1. Introduction. 3.2. Introduction to Transcriptional Regulation. 3.3.
Measuring Gene Expression Profiles. 3.4. Preprocessing of Data. 3.5.
Clustering of Gene Expression Profiles. 3.6. Cluster Validation. 3.7.
Searching for Common Binding Sites of Coregulated Genes. 3.8. Inclusive:
Online Integrated Analysis of Microarray Data. 3.9. Further Integrative
Steps. 3.10. Conclusion. References. 4. Robust Methods for Microarray
Analysis (George S. Davidson, Shawn Martin, Kevin W. Boyack, Brian N.
Wylie, Juanita Martinez, Anthony Aragon, Margaret Werner-Washburne, Mönica
Mosquera-Caro, and Cheryl Willman). 4.1. Introduction. 4.2. Microarray
Experiments and Analysis Methods. 4.3. Unsupervised Methods. 4.4.
Supervised Methods. 4.5. Conclusion. References. 5. In Silico Radiation
Oncology: A Platform for Understanding Cancer Behavior and Optimizing
Radiation Therapy Treatment (G. Stamatakos, D. Dionysiou, and N. Uzunoglu).
5.1. Philosophiae Tumoralis Principia Algorithmica: Algorithmic Principles
of Simulating Cancer on Computer. 5.2. Brief Literature Review. 5.3.
Paradigm of Four-Dimensional Simulation of Tumor Growth and Response to
Radiation Therapy In Vivo. 5.4. Discussion. 5.5. Future Trends. References.
6. Genomewide Motif Identification Using a Dictionary Model (Chiara Sabatti
and Kenneth Lange). 6.1. Introduction. 6.2. Unified Model. 6.3. Algorithms
for Likelihood Evaluation. 6.4. Parameter Estimation via
Minorization-Maximization Algorithm. 6.5. Examples. 6.6. Discussion and
Conclusion. References. 7. Error Control Codes and the Genome (Elebeoba E.
May). 7.1. Error Control and Communication: A Review. 7.3. Reverse
Engineering the Genetic Error Control System. 7.4. Applications of
Biological Coding Theory. References. 8. Complex Life Science Multidatabase
Queries (Zina Ben Miled, Nianhua Li, Yue He, Malika Mahoui, and Omran
Bukhres). 8.1. Introduction. 8.2. Architecture. 8.3. Query Execution Plans.
8.4. Related Work. 8.5. Future Trends. References. 9. Computational
Analysis of Proteins (Dimitrios I. Fotiadis, Yorgos Goletsis, Christos
Lampros, and Costas Papaloukas). 9.1. Introduction: Definitions. 9.2.
Databases. 9.3. Sequence Motifs and Domains. 9.4. Sequence Alignment. 9.5.
Modeling. 9.6. Classification and Prediction. 9.7. Natural Language
Processing. 9.8. Future Trends. References. 10. Computational Analysis of
Interactions Between Tumor and Tumor Suppressor Proteins (E. Pirogova, M.
Akay, and I. Cosic). 10.1. Introduction. 10.2. Methodology: Resonant
Recognition Model. 10.3. Results and Discussions. 10.4. Conclusion.
References. Index. About the Editor.